FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2736693043> ?p ?o ?g. }

• W2736693043 endingPage "2237" @default.
• W2736693043 startingPage "2232" @default.
• W2736693043 abstract "We hypothesized that muscle sympathetic nerve activity (MSNA) during head-up tilt (HUT) would be augmented during exercise-induced (hyperosmotic) dehydration but not isoosmotic dehydration via an oral diuretic. We studied 26 young healthy subjects (7 female, 19 male) divided into three groups: euhydrated (EUH, n = 7), previously exercised in 40°C while maintaining hydration; dehydrated (DEH, n = 10), previously exercised in 40°C during which ~3% of body weight was lost via sweat loss; and diuretic (DIUR, n = 9), a group that did not exercise but lost ~3% of body weight via diuresis (furosemide, 80 mg by mouth). We measured MSNA, heart rate (HR), and blood pressure (BP) during supine rest and 30° and 45° HUT. Plasma volume (PV) decreased similarly in DEH (−8.5 ± 3.3%) and DIUR (−11.4 ± 5.7%) ( P > 0.05). Plasma osmolality was similar between DIUR and EUH (288 ± 4 vs. 284 ± 5 mmol/kg, respectively) but was significantly higher in DEH (299 ± 5 mmol/kg) ( P < 0.05). Mixed-model ANOVA was used with repeated measures on position (HUT) and between-group analysis on condition. HR and MSNA increased in all subjects during HUT (main effect of position; P < 0.05). There was also a significant main effect of group, such that MSNA and HR were higher in DEH compared with DIUR ( P < 0.05). Changes in HR with HUT were larger in both hypovolemic groups compared with EUH ( P < 0.05). The differential HUT response “strategies” in each group suggest a greater role for hypovolemia per se in controlling HR responses during dehydration, and a stronger role for osmolality in control of SNA. NEW & NOTEWORTHY Interactions of volume regulation with control of vascular sympathetic nerve activity (SNA) have important implications for blood pressure regulation. Here, we demonstrate that SNA and heart rate (HR) during hyperosmotic hypovolemia (exercise-induced) were augmented during supine and tilt compared with isoosmotic hypovolemia (diuretic), which primarily augmented the HR response. Our data suggest that hypovolemia per se had a larger role in controlling HR responses, whereas osmolality had a stronger role in control of SNA." @default.
• W2736693043 created "2017-07-31" @default.
• W2736693043 creator A5006738348 @default.
• W2736693043 creator A5008004490 @default.
• W2736693043 creator A5039385175 @default.
• W2736693043 creator A5045387740 @default.
• W2736693043 creator A5046472049 @default.
• W2736693043 creator A5047441794 @default.
• W2736693043 creator A5064940081 @default.
• W2736693043 date "2017-10-01" @default.
• W2736693043 modified "2023-10-05" @default.
• W2736693043 title "Sympathetic neural and hemodynamic responses to head-up tilt during isoosmotic and hyperosmotic hypovolemia" @default.
• W2736693043 cites W1537703620 @default.
• W2736693043 cites W1565667527 @default.
• W2736693043 cites W1613720875 @default.
• W2736693043 cites W1712267234 @default.
• W2736693043 cites W1899598082 @default.
• W2736693043 cites W1984113974 @default.
• W2736693043 cites W1990723779 @default.
• W2736693043 cites W1997497052 @default.
• W2736693043 cites W1998275628 @default.
• W2736693043 cites W2002083458 @default.
• W2736693043 cites W2032110649 @default.
• W2736693043 cites W2049186976 @default.
• W2736693043 cites W2058068599 @default.
• W2736693043 cites W2059225031 @default.
• W2736693043 cites W2090378906 @default.
• W2736693043 cites W2096614949 @default.
• W2736693043 cites W2098807038 @default.
• W2736693043 cites W2104432151 @default.
• W2736693043 cites W2157867781 @default.
• W2736693043 cites W2158323362 @default.
• W2736693043 cites W2158859101 @default.
• W2736693043 cites W2281080948 @default.
• W2736693043 cites W2600900489 @default.
• W2736693043 doi "https://doi.org/10.1152/jn.00403.2017" @default.
• W2736693043 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5626902" @default.
• W2736693043 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28747468" @default.
• W2736693043 hasPublicationYear "2017" @default.
• W2736693043 type Work @default.
• W2736693043 sameAs 2736693043 @default.
• W2736693043 citedByCount "9" @default.
• W2736693043 countsByYear W27366930432019 @default.
• W2736693043 countsByYear W27366930432020 @default.
• W2736693043 countsByYear W27366930432022 @default.
• W2736693043 countsByYear W27366930432023 @default.
• W2736693043 crossrefType "journal-article" @default.
• W2736693043 hasAuthorship W2736693043A5006738348 @default.
• W2736693043 hasAuthorship W2736693043A5008004490 @default.
• W2736693043 hasAuthorship W2736693043A5039385175 @default.
• W2736693043 hasAuthorship W2736693043A5045387740 @default.
• W2736693043 hasAuthorship W2736693043A5046472049 @default.
• W2736693043 hasAuthorship W2736693043A5047441794 @default.
• W2736693043 hasAuthorship W2736693043A5064940081 @default.
• W2736693043 hasBestOaLocation W27366930431 @default.
• W2736693043 hasConcept C125567185 @default.
• W2736693043 hasConcept C126322002 @default.
• W2736693043 hasConcept C134018914 @default.
• W2736693043 hasConcept C178853913 @default.
• W2736693043 hasConcept C185592680 @default.
• W2736693043 hasConcept C2776533406 @default.
• W2736693043 hasConcept C2777953023 @default.
• W2736693043 hasConcept C2777955127 @default.
• W2736693043 hasConcept C2779918671 @default.
• W2736693043 hasConcept C2781309813 @default.
• W2736693043 hasConcept C42219234 @default.
• W2736693043 hasConcept C71924100 @default.
• W2736693043 hasConcept C84393581 @default.
• W2736693043 hasConceptScore W2736693043C125567185 @default.
• W2736693043 hasConceptScore W2736693043C126322002 @default.
• W2736693043 hasConceptScore W2736693043C134018914 @default.
• W2736693043 hasConceptScore W2736693043C178853913 @default.
• W2736693043 hasConceptScore W2736693043C185592680 @default.
• W2736693043 hasConceptScore W2736693043C2776533406 @default.
• W2736693043 hasConceptScore W2736693043C2777953023 @default.
• W2736693043 hasConceptScore W2736693043C2777955127 @default.
• W2736693043 hasConceptScore W2736693043C2779918671 @default.
• W2736693043 hasConceptScore W2736693043C2781309813 @default.
• W2736693043 hasConceptScore W2736693043C42219234 @default.
• W2736693043 hasConceptScore W2736693043C71924100 @default.
• W2736693043 hasConceptScore W2736693043C84393581 @default.
• W2736693043 hasIssue "4" @default.
• W2736693043 hasLocation W27366930431 @default.
• W2736693043 hasLocation W27366930432 @default.
• W2736693043 hasLocation W27366930433 @default.
• W2736693043 hasLocation W27366930434 @default.
• W2736693043 hasOpenAccess W2736693043 @default.
• W2736693043 hasPrimaryLocation W27366930431 @default.
• W2736693043 hasRelatedWork W112590946 @default.
• W2736693043 hasRelatedWork W1995192322 @default.
• W2736693043 hasRelatedWork W2014570142 @default.
• W2736693043 hasRelatedWork W2119698783 @default.
• W2736693043 hasRelatedWork W2736693043 @default.
• W2736693043 hasRelatedWork W2748952813 @default.
• W2736693043 hasRelatedWork W2765736107 @default.
• W2736693043 hasRelatedWork W3132942621 @default.
• W2736693043 hasRelatedWork W4378649561 @default.
• W2736693043 hasRelatedWork W73303660 @default.

• next