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- W2736762493 abstract "Gut microbiota has been revealed to play an important role in various health conditions, and recent studies have suggested the modulation of gut microbiota as a therapeutic strategy. There is no effective treatment of norovirus infection, though vitamin A has been suggested to have an antiviral effect in an epidemiological study. We demonstrated that vitamin A significantly inhibited murine norovirus replication. Vitamin A supplementation significantly increased the abundance of Lactobacillus sp. during norovirus infection, which played a crucial role in antiviral efficacy, inhibiting murine norovirus. Therefore, we elaborated the antiviral effect of vitamin A via modulation of gut microbiota. Furthermore, we suggest a novel strategy, using potential probiotics, as having a protective and therapeutic effect on noroviral infection." @default.
- W2736762493 created "2017-07-31" @default.
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- W2736762493 date "2017-08-03" @default.
- W2736762493 modified "2023-10-18" @default.
- W2736762493 title "New perspectives regarding the antiviral effect of vitamin A on norovirus using modulation of gut microbiota" @default.
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- W2736762493 doi "https://doi.org/10.1080/19490976.2017.1353842" @default.
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