Matches in SemOpenAlex for { <https://semopenalex.org/work/W2737228712> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2737228712 abstract "Certain specific antigens, which behave as oncoproteins, are present in normal fetal/neonatal developing brain. It was demonstrated that a convergence exists between ontogenesis and onco-genesis. The most malignant example of central nervous system neoplasia is glioblastoma multiforme. The biomarker – oncoprotein - characteristic of glial fetal and tumoral cells, but not neuronal cells, is IGF-I. For this reason, for therapy purpose, the arrest of IGF-I synthesis in cancer glial cells of glioblastoma was performed using in vitro anti – gene anti IGF-I strategy (IGF-I antisense /triple helix, AS/TH). The created AS/TH cells, became immunogenic and expressed MHC-I, B71 antigens. The AS/TH cells while injected in glioblastoma patients, induced the antitumor immune response and stopped the progression of tumor development. The survival of treated glioblastoma patients reached 2 years, and in some cases, up to 3-4 years. The established Anti - Gene IGF-I cancer immunotherapy was introduced in USA, Europe, China and Latin America." @default.
- W2737228712 created "2017-07-31" @default.
- W2737228712 creator A5088240323 @default.
- W2737228712 date "2017-04-04" @default.
- W2737228712 modified "2023-09-24" @default.
- W2737228712 title "Cancer Immunogene Therapy" @default.
- W2737228712 hasPublicationYear "2017" @default.
- W2737228712 type Work @default.
- W2737228712 sameAs 2737228712 @default.
- W2737228712 citedByCount "0" @default.
- W2737228712 crossrefType "book" @default.
- W2737228712 hasAuthorship W2737228712A5088240323 @default.
- W2737228712 hasConcept C104317684 @default.
- W2737228712 hasConcept C111599444 @default.
- W2737228712 hasConcept C121608353 @default.
- W2737228712 hasConcept C147483822 @default.
- W2737228712 hasConcept C167672396 @default.
- W2737228712 hasConcept C203014093 @default.
- W2737228712 hasConcept C2777701055 @default.
- W2737228712 hasConcept C502942594 @default.
- W2737228712 hasConcept C54355233 @default.
- W2737228712 hasConcept C71924100 @default.
- W2737228712 hasConcept C86803240 @default.
- W2737228712 hasConcept C8891405 @default.
- W2737228712 hasConceptScore W2737228712C104317684 @default.
- W2737228712 hasConceptScore W2737228712C111599444 @default.
- W2737228712 hasConceptScore W2737228712C121608353 @default.
- W2737228712 hasConceptScore W2737228712C147483822 @default.
- W2737228712 hasConceptScore W2737228712C167672396 @default.
- W2737228712 hasConceptScore W2737228712C203014093 @default.
- W2737228712 hasConceptScore W2737228712C2777701055 @default.
- W2737228712 hasConceptScore W2737228712C502942594 @default.
- W2737228712 hasConceptScore W2737228712C54355233 @default.
- W2737228712 hasConceptScore W2737228712C71924100 @default.
- W2737228712 hasConceptScore W2737228712C86803240 @default.
- W2737228712 hasConceptScore W2737228712C8891405 @default.
- W2737228712 hasLocation W27372287121 @default.
- W2737228712 hasOpenAccess W2737228712 @default.
- W2737228712 hasPrimaryLocation W27372287121 @default.
- W2737228712 hasRelatedWork W129710973 @default.
- W2737228712 hasRelatedWork W181480165 @default.
- W2737228712 hasRelatedWork W1976659174 @default.
- W2737228712 hasRelatedWork W2009914447 @default.
- W2737228712 hasRelatedWork W2024576444 @default.
- W2737228712 hasRelatedWork W2037128246 @default.
- W2737228712 hasRelatedWork W2037265356 @default.
- W2737228712 hasRelatedWork W2050740124 @default.
- W2737228712 hasRelatedWork W2088538447 @default.
- W2737228712 hasRelatedWork W2134754781 @default.
- W2737228712 hasRelatedWork W2141099036 @default.
- W2737228712 hasRelatedWork W2178308715 @default.
- W2737228712 hasRelatedWork W2538680458 @default.
- W2737228712 hasRelatedWork W2587564559 @default.
- W2737228712 hasRelatedWork W2790865199 @default.
- W2737228712 hasRelatedWork W2965262659 @default.
- W2737228712 hasRelatedWork W2965323336 @default.
- W2737228712 hasRelatedWork W308174641 @default.
- W2737228712 hasRelatedWork W3160217129 @default.
- W2737228712 hasRelatedWork W3173590328 @default.
- W2737228712 isParatext "false" @default.
- W2737228712 isRetracted "false" @default.
- W2737228712 magId "2737228712" @default.
- W2737228712 workType "book" @default.