FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2737534949> ?p ?o ?g. }

• W2737534949 endingPage "314" @default.
• W2737534949 startingPage "310" @default.
• W2737534949 abstract "Carbapenemase-producing Aeromonas spp. are of great concern in healthcare settings and are also known to acquire clinically relevant resistance genes. In this study, carbapenem-non-susceptible Aeromonas isolates were characterised for their molecular mechanisms of resistance. Among 180 Aeromonas isolates, 10 carbapenem-non-susceptible isolates were selected based on their antimicrobial susceptibility profile. Carbapenemase production was investigated by the CarbaNP test. ESBL-, AmpC- and carbapenemase-encoding genes were screened by PCR. Isolates VBF557 and VBF856 with high MICs for imipenem were selected for whole-genome sequencing (WGS). Conjugation experiments were performed to determine the transmissibility of resistance. WGS remarkably revealed the presence of class D β-lactamases (AmpS/AmpH), class C β-lactamases and class B2 metallo-β-lactamase (cphA3) in VBF557. In contrast, VBF856 had multiple resistance genes coding for aminoglycoside, sulphonamide, carbapenem (blaOXA-181 class D β-lactamase), macrolide, fluoroquinolone, rifampicin, phenicol, tetracycline and trimethoprim resistance. This is the first global report of blaOXA-181 in Aeromonas spp. Interestingly, blaOXA-181 was identified in association with transposon Tn2013 in plasmid pKP3-A. Additionally, an IncQ2 plasmid with qnrS2 was identified. Among the tested isolates, VBF1116 and VBF888 possessed blaNDM and blaVEB, respectively, by PCR. None of the other isolates harboured any tested β-lactamase genes. The resistance gene was transmissible in the presence of imipenem. Presence of such resistance genes in plasmids further adds complexity for control of spread of carbapenem resistance. This study reveals the emergence of carbapenem resistance among Aeromonas spp. and the importance of mobile genetic elements such as plasmids in interchanging resistance determinants between species." @default.
• W2737534949 created "2017-07-31" @default.
• W2737534949 creator A5002639768 @default.
• W2737534949 creator A5017282047 @default.
• W2737534949 creator A5038846881 @default.
• W2737534949 creator A5039797179 @default.
• W2737534949 creator A5050926527 @default.
• W2737534949 creator A5055559660 @default.
• W2737534949 creator A5077907796 @default.
• W2737534949 date "2017-09-01" @default.
• W2737534949 modified "2023-10-16" @default.
• W2737534949 title "First report of bla OXA-181 -mediated carbapenem resistance in Aeromonas caviae in association with pKP3-A: Threat for rapid dissemination" @default.
• W2737534949 cites W1564048008 @default.
• W2737534949 cites W1865009538 @default.
• W2737534949 cites W1967485743 @default.
• W2737534949 cites W1974069002 @default.
• W2737534949 cites W1986708244 @default.
• W2737534949 cites W1991430604 @default.
• W2737534949 cites W2004548026 @default.
• W2737534949 cites W2011262200 @default.
• W2737534949 cites W2057684478 @default.
• W2737534949 cites W2063756105 @default.
• W2737534949 cites W2082359880 @default.
• W2737534949 cites W2097195614 @default.
• W2737534949 cites W2099001508 @default.
• W2737534949 cites W2100147853 @default.
• W2737534949 cites W2101187263 @default.
• W2737534949 cites W2104172130 @default.
• W2737534949 cites W2111802525 @default.
• W2737534949 cites W2137269542 @default.
• W2737534949 cites W2141888371 @default.
• W2737534949 cites W2142428670 @default.
• W2737534949 cites W2151329795 @default.
• W2737534949 cites W2156699314 @default.
• W2737534949 cites W2158619106 @default.
• W2737534949 cites W2173537513 @default.
• W2737534949 cites W2186590720 @default.
• W2737534949 cites W2266161997 @default.
• W2737534949 cites W2285162425 @default.
• W2737534949 cites W4231865638 @default.
• W2737534949 doi "https://doi.org/10.1016/j.jgar.2017.07.006" @default.
• W2737534949 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28743649" @default.
• W2737534949 hasPublicationYear "2017" @default.
• W2737534949 type Work @default.
• W2737534949 sameAs 2737534949 @default.
• W2737534949 citedByCount "21" @default.
• W2737534949 countsByYear W27375349492018 @default.
• W2737534949 countsByYear W27375349492019 @default.
• W2737534949 countsByYear W27375349492020 @default.
• W2737534949 countsByYear W27375349492021 @default.
• W2737534949 countsByYear W27375349492022 @default.
• W2737534949 countsByYear W27375349492023 @default.
• W2737534949 crossrefType "journal-article" @default.
• W2737534949 hasAuthorship W2737534949A5002639768 @default.
• W2737534949 hasAuthorship W2737534949A5017282047 @default.
• W2737534949 hasAuthorship W2737534949A5038846881 @default.
• W2737534949 hasAuthorship W2737534949A5039797179 @default.
• W2737534949 hasAuthorship W2737534949A5050926527 @default.
• W2737534949 hasAuthorship W2737534949A5055559660 @default.
• W2737534949 hasAuthorship W2737534949A5077907796 @default.
• W2737534949 hasConcept C104317684 @default.
• W2737534949 hasConcept C132533263 @default.
• W2737534949 hasConcept C22744801 @default.
• W2737534949 hasConcept C2776685102 @default.
• W2737534949 hasConcept C2777935563 @default.
• W2737534949 hasConcept C2779631663 @default.
• W2737534949 hasConcept C2780313371 @default.
• W2737534949 hasConcept C501593827 @default.
• W2737534949 hasConcept C523546767 @default.
• W2737534949 hasConcept C54355233 @default.
• W2737534949 hasConcept C86803240 @default.
• W2737534949 hasConcept C89423630 @default.
• W2737534949 hasConcept C94665300 @default.
• W2737534949 hasConceptScore W2737534949C104317684 @default.
• W2737534949 hasConceptScore W2737534949C132533263 @default.
• W2737534949 hasConceptScore W2737534949C22744801 @default.
• W2737534949 hasConceptScore W2737534949C2776685102 @default.
• W2737534949 hasConceptScore W2737534949C2777935563 @default.
• W2737534949 hasConceptScore W2737534949C2779631663 @default.
• W2737534949 hasConceptScore W2737534949C2780313371 @default.
• W2737534949 hasConceptScore W2737534949C501593827 @default.
• W2737534949 hasConceptScore W2737534949C523546767 @default.
• W2737534949 hasConceptScore W2737534949C54355233 @default.
• W2737534949 hasConceptScore W2737534949C86803240 @default.
• W2737534949 hasConceptScore W2737534949C89423630 @default.
• W2737534949 hasConceptScore W2737534949C94665300 @default.
• W2737534949 hasLocation W27375349491 @default.
• W2737534949 hasLocation W27375349492 @default.
• W2737534949 hasOpenAccess W2737534949 @default.
• W2737534949 hasPrimaryLocation W27375349491 @default.
• W2737534949 hasRelatedWork W1967730663 @default.
• W2737534949 hasRelatedWork W1970948691 @default.
• W2737534949 hasRelatedWork W2080257808 @default.
• W2737534949 hasRelatedWork W2326035127 @default.
• W2737534949 hasRelatedWork W2613338243 @default.
• W2737534949 hasRelatedWork W2737534949 @default.
• W2737534949 hasRelatedWork W2790937404 @default.
• W2737534949 hasRelatedWork W3031941101 @default.

• next