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• W2738051399 abstract "Significance The human face is extraordinarily variable, and the extreme similarity of the faces of identical twins indicates that most of this variability is genetically determined. We have devised an approach to increase the chance of identifying specific large genetic effects on particular facial features, by choosing features with high heritability and selecting individuals with relatively extreme facial phenotypes for comparison with a control population. This has yielded three specific and replicated genetic variants, two for features of facial profiles, and one for the region around the eyes. Further application of these methods should enable the understanding, eventually at the molecular level, of the nature of this extraordinary genetic variability, which is such an important feature of our everyday human interactions." @default.
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• W2738051399 date "2018-01-04" @default.
• W2738051399 modified "2023-10-16" @default.
• W2738051399 title "Genetics of the human face: Identification of large-effect single gene variants" @default.
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• W2738051399 doi "https://doi.org/10.1073/pnas.1708207114" @default.
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