Matches in SemOpenAlex for { <https://semopenalex.org/work/W2738346014> ?p ?o ?g. }
- W2738346014 endingPage "189.e3" @default.
- W2738346014 startingPage "181" @default.
- W2738346014 abstract "Centromeres are specified and maintained by sequence-independent epigenetic mechanisms through the incorporation of CENP-A into centromeres. Given that CENP-A incorporation requires the Mis18 complex to be in the centromere region, it is necessary to precisely understand how the Mis18 complex localizes to the centromere region. Here, we showed that centromere localization of the Mis18 complex depends on CENP-A, but not CENP-C or CENP-T, in chicken DT40 cells. Furthermore, we demonstrated that M18BP1/KNL2, a member of the Mis18 complex, contained the CENP-C-like motif in chicken and other vertebrates, which is essential for centromere localization and M18BP1/KNL2 function in DT40 cells. We also showed that in vitro reconstituted CENP-A nucleosome, but not H3 nucleosome, bound to the CENP-C-like motif containing M18BP1/KNL2. Based on these results, we conclude that M18BP1/KNL2 is essential for centromere formation through direct binding to CENP-A nucleosome in non-mammalian vertebrates. This explains how new CENP-A recognizes the centromere position." @default.
- W2738346014 created "2017-07-31" @default.
- W2738346014 creator A5003389108 @default.
- W2738346014 creator A5004903523 @default.
- W2738346014 creator A5016892353 @default.
- W2738346014 creator A5018553659 @default.
- W2738346014 creator A5023921886 @default.
- W2738346014 creator A5036888639 @default.
- W2738346014 creator A5070212943 @default.
- W2738346014 creator A5089786709 @default.
- W2738346014 date "2017-07-01" @default.
- W2738346014 modified "2023-10-13" @default.
- W2738346014 title "Association of M18BP1/KNL2 with CENP-A Nucleosome Is Essential for Centromere Formation in Non-mammalian Vertebrates" @default.
- W2738346014 cites W1574351523 @default.
- W2738346014 cites W1965813899 @default.
- W2738346014 cites W1970549330 @default.
- W2738346014 cites W1993824700 @default.
- W2738346014 cites W2004910827 @default.
- W2738346014 cites W2005708736 @default.
- W2738346014 cites W2013711216 @default.
- W2738346014 cites W2014270114 @default.
- W2738346014 cites W2029503499 @default.
- W2738346014 cites W2034482404 @default.
- W2738346014 cites W2040904248 @default.
- W2738346014 cites W2041773888 @default.
- W2738346014 cites W2062279301 @default.
- W2738346014 cites W2074286944 @default.
- W2738346014 cites W2085407032 @default.
- W2738346014 cites W2086329703 @default.
- W2738346014 cites W2091618203 @default.
- W2738346014 cites W2092650602 @default.
- W2738346014 cites W2103089522 @default.
- W2738346014 cites W2103703088 @default.
- W2738346014 cites W2106413052 @default.
- W2738346014 cites W2126316501 @default.
- W2738346014 cites W2133800605 @default.
- W2738346014 cites W2138763599 @default.
- W2738346014 cites W2143730235 @default.
- W2738346014 cites W2145579024 @default.
- W2738346014 cites W2147290892 @default.
- W2738346014 cites W2159079025 @default.
- W2738346014 cites W2161314996 @default.
- W2738346014 cites W2166056574 @default.
- W2738346014 cites W2175830921 @default.
- W2738346014 cites W2201981761 @default.
- W2738346014 cites W2209738096 @default.
- W2738346014 cites W2240680061 @default.
- W2738346014 cites W2287127061 @default.
- W2738346014 cites W2288886458 @default.
- W2738346014 cites W2312495072 @default.
- W2738346014 cites W2546896382 @default.
- W2738346014 cites W2567029775 @default.
- W2738346014 cites W2568187881 @default.
- W2738346014 cites W2569419841 @default.
- W2738346014 cites W2738572927 @default.
- W2738346014 doi "https://doi.org/10.1016/j.devcel.2017.06.019" @default.
- W2738346014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28743004" @default.
- W2738346014 hasPublicationYear "2017" @default.
- W2738346014 type Work @default.
- W2738346014 sameAs 2738346014 @default.
- W2738346014 citedByCount "53" @default.
- W2738346014 countsByYear W27383460142017 @default.
- W2738346014 countsByYear W27383460142018 @default.
- W2738346014 countsByYear W27383460142019 @default.
- W2738346014 countsByYear W27383460142020 @default.
- W2738346014 countsByYear W27383460142021 @default.
- W2738346014 countsByYear W27383460142022 @default.
- W2738346014 countsByYear W27383460142023 @default.
- W2738346014 crossrefType "journal-article" @default.
- W2738346014 hasAuthorship W2738346014A5003389108 @default.
- W2738346014 hasAuthorship W2738346014A5004903523 @default.
- W2738346014 hasAuthorship W2738346014A5016892353 @default.
- W2738346014 hasAuthorship W2738346014A5018553659 @default.
- W2738346014 hasAuthorship W2738346014A5023921886 @default.
- W2738346014 hasAuthorship W2738346014A5036888639 @default.
- W2738346014 hasAuthorship W2738346014A5070212943 @default.
- W2738346014 hasAuthorship W2738346014A5089786709 @default.
- W2738346014 hasBestOaLocation W27383460141 @default.
- W2738346014 hasConcept C104317684 @default.
- W2738346014 hasConcept C2776745794 @default.
- W2738346014 hasConcept C30481170 @default.
- W2738346014 hasConcept C54355233 @default.
- W2738346014 hasConcept C552990157 @default.
- W2738346014 hasConcept C63491729 @default.
- W2738346014 hasConcept C64927066 @default.
- W2738346014 hasConcept C84772758 @default.
- W2738346014 hasConcept C86803240 @default.
- W2738346014 hasConcept C95444343 @default.
- W2738346014 hasConceptScore W2738346014C104317684 @default.
- W2738346014 hasConceptScore W2738346014C2776745794 @default.
- W2738346014 hasConceptScore W2738346014C30481170 @default.
- W2738346014 hasConceptScore W2738346014C54355233 @default.
- W2738346014 hasConceptScore W2738346014C552990157 @default.
- W2738346014 hasConceptScore W2738346014C63491729 @default.
- W2738346014 hasConceptScore W2738346014C64927066 @default.
- W2738346014 hasConceptScore W2738346014C84772758 @default.
- W2738346014 hasConceptScore W2738346014C86803240 @default.
- W2738346014 hasConceptScore W2738346014C95444343 @default.