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• W2738451851 abstract "// Mingsheng Cai 2 , Zongmin Liao 2 , Tao Chen 2 , Ping Wang 2 , Xingmei Zou 2 , Yuanfang Wang 2 , Zuo Xu 2 , Si Jiang 2 , Jinlu Huang 3 , Daixiong Chen 2 , Tao Peng 2 , Gengde Hong 4 and Meili Li 1, 2 1 Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, Guangdong, China 2 Department of Pathogenic Biology and Immunology, Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou 511436, Guangdong, China 3 Guangdong Haid Group Co., Ltd., Guangzhou 511400, Guandong, China 4 The Third Clinical School of Guangzhou Medical University, Guangzhou 510150, Guangdong, China Correspondence to: Meili Li, email: meili_2011@hotmail.com Keywords: Epstein-Barr virus, subcellular localization, live cell microscopy Received: February 03, 2017      Accepted: June 29, 2017      Published: July 25, 2017 ABSTRACT Epstein-Barr virus (EBV) is the pathogenic factor of numerous human tumors, yet certain of its encoded proteins have not been studied. As a first step for functional identification, we presented the construction of a library of expression constructs for most of the EBV encoded proteins and an explicit subcellular localization map of 81 proteins encoded by EBV in mammalian cells. Viral open reading frames were fused with enhanced yellow fluorescent protein (EYFP) tag in eukaryotic expression plasmid then expressed in COS-7 live cells, and protein localizations were observed by fluorescence microscopy. As results, 34.57% (28 proteins) of all proteins showed pan-nuclear or subnuclear localization, 39.51% (32 proteins) exhibitted pan-cytoplasmic or subcytoplasmic localization, and 25.93% (21 proteins) were found in both the nucleus and cytoplasm. Interestingly, most envelope proteins presented pan-cytoplasmic or membranous localization, and most capsid proteins displayed enriched or complete localization in the nucleus, indicating that the subcellular localization of specific proteins are associated with their roles during viral replication. Taken together, the subcellular localization map of EBV proteins in live cells may lay the foundation for further illustrating the functions of EBV-encoded genes in human diseases especially in its relevant tumors." @default.
• W2738451851 created "2017-07-31" @default.
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• W2738451851 date "2017-07-25" @default.
• W2738451851 modified "2023-09-24" @default.
• W2738451851 title "Characterization of the subcellular localization of Epstein-Barr virus encoded proteins in live cells" @default.
• W2738451851 cites W1489924954 @default.
• W2738451851 cites W1507472194 @default.
• W2738451851 cites W1512347279 @default.
• W2738451851 cites W1529003390 @default.
• W2738451851 cites W1561325768 @default.
• W2738451851 cites W1578954095 @default.
• W2738451851 cites W1581034919 @default.
• W2738451851 cites W1661741137 @default.
• W2738451851 cites W1755591780 @default.
• W2738451851 cites W1761765142 @default.
• W2738451851 cites W1841774701 @default.
• W2738451851 cites W1850833784 @default.
• W2738451851 cites W1883897672 @default.
• W2738451851 cites W1966948366 @default.
• W2738451851 cites W1969906232 @default.
• W2738451851 cites W1972186498 @default.
• W2738451851 cites W1973640489 @default.
• W2738451851 cites W1975638678 @default.
• W2738451851 cites W1976733669 @default.
• W2738451851 cites W1983658440 @default.
• W2738451851 cites W1988611525 @default.
• W2738451851 cites W1996339554 @default.
• W2738451851 cites W1999875242 @default.
• W2738451851 cites W2000714852 @default.
• W2738451851 cites W2002033363 @default.
• W2738451851 cites W2008747535 @default.
• W2738451851 cites W2011257491 @default.
• W2738451851 cites W2011993572 @default.
• W2738451851 cites W2013125831 @default.
• W2738451851 cites W2019158040 @default.
• W2738451851 cites W2027952293 @default.
• W2738451851 cites W2042699304 @default.
• W2738451851 cites W2048821779 @default.
• W2738451851 cites W2049711896 @default.
• W2738451851 cites W2050129013 @default.
• W2738451851 cites W2057267741 @default.
• W2738451851 cites W2068118422 @default.
• W2738451851 cites W2070354169 @default.
• W2738451851 cites W2080385928 @default.
• W2738451851 cites W2084268900 @default.
• W2738451851 cites W2088954361 @default.
• W2738451851 cites W20894727 @default.
• W2738451851 cites W2089651001 @default.
• W2738451851 cites W2095024877 @default.
• W2738451851 cites W2098818179 @default.
• W2738451851 cites W2102489836 @default.
• W2738451851 cites W2103480414 @default.
• W2738451851 cites W2119281455 @default.
• W2738451851 cites W2120877740 @default.
• W2738451851 cites W2121093542 @default.
• W2738451851 cites W2125063594 @default.
• W2738451851 cites W2137409417 @default.
• W2738451851 cites W2138241311 @default.
• W2738451851 cites W2139820569 @default.
• W2738451851 cites W2140097637 @default.
• W2738451851 cites W2140662587 @default.
• W2738451851 cites W2141301893 @default.
• W2738451851 cites W2142617008 @default.
• W2738451851 cites W2143369415 @default.
• W2738451851 cites W2144559796 @default.
• W2738451851 cites W2147550337 @default.
• W2738451851 cites W2148586573 @default.
• W2738451851 cites W2149198894 @default.
• W2738451851 cites W2149655243 @default.
• W2738451851 cites W2152399726 @default.
• W2738451851 cites W2153307268 @default.
• W2738451851 cites W2154010136 @default.
• W2738451851 cites W2158813218 @default.
• W2738451851 cites W2160051891 @default.
• W2738451851 cites W2162250757 @default.
• W2738451851 cites W2163610150 @default.
• W2738451851 cites W2164410061 @default.
• W2738451851 cites W2166719666 @default.
• W2738451851 cites W2168774029 @default.
• W2738451851 cites W2169360576 @default.
• W2738451851 cites W2169805130 @default.
• W2738451851 cites W2183711318 @default.
• W2738451851 cites W2184454467 @default.
• W2738451851 cites W2255964425 @default.
• W2738451851 cites W2260923959 @default.

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