Matches in SemOpenAlex for { <https://semopenalex.org/work/W2738567488> ?p ?o ?g. }
- W2738567488 endingPage "2995" @default.
- W2738567488 startingPage "2983" @default.
- W2738567488 abstract "ABSTRACT Fusarium keratitis is a destructive eye infection that is difficult to treat and results in poor outcome. In tropical and subtropical areas, the infection is relatively common and associated with trauma or chronic eye diseases. However, in recent years, an increased incidence has been reported in temperate climate regions. At the German National Reference Center, we have observed a steady increase in case numbers since 2014. Here, we present the first German case series of eye infections with Fusarium species. We identified Fusarium isolates from the eye or eye-related material from 22 patients in 2014 and 2015. Thirteen isolates belonged to the Fusarium solani species complex (FSSC), 6 isolates belonged to the Fusarium oxysporum species complex (FOSC), and three isolates belonged to the Fusarium fujikuroi species complex (FFSC). FSSC was isolated in 13 of 15 (85%) definite infections and FOSC in 3 of 4 (75%) definite contaminations. Furthermore, diagnosis from contact lens swabs or a culture of contact lens solution turned out to be highly unreliable. FSSC isolates differed from FOSC and FFSC by a distinctly higher MIC for terbinafine. Outcome was often adverse, with 10 patients requiring keratoplasty or enucleation. The use of natamycin as the most effective agent against keratitis caused by filamentous fungi was rare in Germany, possibly due to restricted availability. Keratitis caused by Fusarium spp. (usually FSSC) appears to be a relevant clinical problem in Germany, with the use of contact lenses as the predominant risk factor. Its outcome is often adverse." @default.
- W2738567488 created "2017-07-31" @default.
- W2738567488 creator A5005890332 @default.
- W2738567488 creator A5014845191 @default.
- W2738567488 creator A5027786740 @default.
- W2738567488 creator A5041454251 @default.
- W2738567488 creator A5044917199 @default.
- W2738567488 creator A5058652117 @default.
- W2738567488 creator A5066938158 @default.
- W2738567488 creator A5070655188 @default.
- W2738567488 creator A5089607608 @default.
- W2738567488 creator A5089641639 @default.
- W2738567488 date "2017-10-01" @default.
- W2738567488 modified "2023-09-28" @default.
- W2738567488 title "Fusarium Keratitis in Germany" @default.
- W2738567488 cites W1010427666 @default.
- W2738567488 cites W12653918 @default.
- W2738567488 cites W1760582675 @default.
- W2738567488 cites W1883639496 @default.
- W2738567488 cites W1908550224 @default.
- W2738567488 cites W1974166687 @default.
- W2738567488 cites W1975231832 @default.
- W2738567488 cites W1976835744 @default.
- W2738567488 cites W1983978508 @default.
- W2738567488 cites W1984461614 @default.
- W2738567488 cites W1985951348 @default.
- W2738567488 cites W1990364433 @default.
- W2738567488 cites W1990384969 @default.
- W2738567488 cites W1995954153 @default.
- W2738567488 cites W2001276323 @default.
- W2738567488 cites W2003199422 @default.
- W2738567488 cites W2015015883 @default.
- W2738567488 cites W2017131106 @default.
- W2738567488 cites W2017392894 @default.
- W2738567488 cites W2019637910 @default.
- W2738567488 cites W2032365046 @default.
- W2738567488 cites W2032776860 @default.
- W2738567488 cites W2036030199 @default.
- W2738567488 cites W2042213457 @default.
- W2738567488 cites W2048720203 @default.
- W2738567488 cites W2052512898 @default.
- W2738567488 cites W2058571383 @default.
- W2738567488 cites W2067086379 @default.
- W2738567488 cites W2067121432 @default.
- W2738567488 cites W2075845898 @default.
- W2738567488 cites W2082361953 @default.
- W2738567488 cites W2083015725 @default.
- W2738567488 cites W2086627549 @default.
- W2738567488 cites W2091330203 @default.
- W2738567488 cites W2095069870 @default.
- W2738567488 cites W2099295686 @default.
- W2738567488 cites W2103617967 @default.
- W2738567488 cites W2109572389 @default.
- W2738567488 cites W2116149411 @default.
- W2738567488 cites W2116582646 @default.
- W2738567488 cites W2121417202 @default.
- W2738567488 cites W2128822001 @default.
- W2738567488 cites W2130951551 @default.
- W2738567488 cites W2136732803 @default.
- W2738567488 cites W2138437709 @default.
- W2738567488 cites W2140467714 @default.
- W2738567488 cites W2142652326 @default.
- W2738567488 cites W2145621004 @default.
- W2738567488 cites W2151790183 @default.
- W2738567488 cites W2156509535 @default.
- W2738567488 cites W2157068508 @default.
- W2738567488 cites W2157563352 @default.
- W2738567488 cites W2328480632 @default.
- W2738567488 cites W2331596219 @default.
- W2738567488 cites W2339582982 @default.
- W2738567488 cites W2345212023 @default.
- W2738567488 cites W2349539459 @default.
- W2738567488 cites W2411482302 @default.
- W2738567488 cites W2411800135 @default.
- W2738567488 cites W2412273163 @default.
- W2738567488 cites W2461817479 @default.
- W2738567488 cites W4244078919 @default.
- W2738567488 doi "https://doi.org/10.1128/jcm.00649-17" @default.
- W2738567488 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5625384" @default.
- W2738567488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28747368" @default.
- W2738567488 hasPublicationYear "2017" @default.
- W2738567488 type Work @default.
- W2738567488 sameAs 2738567488 @default.
- W2738567488 citedByCount "60" @default.
- W2738567488 countsByYear W27385674882018 @default.
- W2738567488 countsByYear W27385674882019 @default.
- W2738567488 countsByYear W27385674882020 @default.
- W2738567488 countsByYear W27385674882021 @default.
- W2738567488 countsByYear W27385674882022 @default.
- W2738567488 countsByYear W27385674882023 @default.
- W2738567488 crossrefType "journal-article" @default.
- W2738567488 hasAuthorship W2738567488A5005890332 @default.
- W2738567488 hasAuthorship W2738567488A5014845191 @default.
- W2738567488 hasAuthorship W2738567488A5027786740 @default.
- W2738567488 hasAuthorship W2738567488A5041454251 @default.
- W2738567488 hasAuthorship W2738567488A5044917199 @default.
- W2738567488 hasAuthorship W2738567488A5058652117 @default.
- W2738567488 hasAuthorship W2738567488A5066938158 @default.