FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2738798927> ?p ?o ?g. }

• W2738798927 endingPage "370" @default.
• W2738798927 startingPage "359" @default.
• W2738798927 abstract "ABSTRACT Streptococcus pneumoniae , a common human pathogen, colonizes the nasopharynx and causes diseases including acute otitis media (AOM). Herein, pneumococcal serotype distributions in children before and after PCV7 vaccination and in patients with pneumococcal disease in Siberian Russia (Krasnoyarsk) are reported. Analyses included antimicrobial susceptibility testing, sequence typing (ST), pulsed field gel electrophoresis, virulence‐related surface protein gene (VSG) typing with novel primers and structural analysis by scanning electron microscopy. In healthy children (HC) prior to administration of PCV7, drug‐susceptible serotype23F/ST1500 was a major pneumococcal genotype. In the PCV7 trial, multidrug‐resistant serotype19A/ST320 emerged in vaccinees after PCV7, exhibiting a PCV7‐induced serotype replacement. Multidrug‐resistant serotype19A/ST320 was evident in patients with AOM. Community‐acquired pneumonia (CAP) isolates showed genetic similarities to the AOM (ST320) genotype, constituting a common non‐invasive AOM–CAP group. In contrast, meningitis isolates were more divergent. Overall, 25 ST types were identified; five (20%) of which were Krasnoyarsk‐native. Regarding VSGs, PI‐1 ( rlrA / rrgB ), PI‐2 ( pitA / B ), psrP and cbpA were present at 54.3%, 38.6%, 48.6%, and 95.7%, respectively, with two major VSG content types, PI‐1 − /PI‐2 − / psrP + / cbpA + and PI‐1 + /PI‐2 + / psrP ‐ / cbpA + , being found for HC and non‐invasive diseases, respectively. A major clone of serotype19A/ST320 (PI‐1 + /PI‐2 + ) produced the longest pneumococcal wire (pilus) structures in colonies. ST1016 (PI‐1 − /PI‐2 − ) in HC had HEp‐2 cell‐adherent pili. These results suggest that serotype19A/ST320 and related genotypes, with the VSG content type PI‐1 + /PI‐2 + / psrP − / cbpA + , emerged in vaccinees after PCV7 in Siberia, accompanying diseases in non‐vaccinated children, and that some genotypes (serotypes19A/ST320 and 18/ST1016) produced novel pneumococcal structures, predicting their roles in colony formation and adherence." @default.
• W2738798927 created "2017-07-31" @default.
• W2738798927 creator A5016679829 @default.
• W2738798927 creator A5023589163 @default.
• W2738798927 creator A5033858443 @default.
• W2738798927 creator A5034621712 @default.
• W2738798927 creator A5042762695 @default.
• W2738798927 creator A5052364651 @default.
• W2738798927 creator A5058422953 @default.
• W2738798927 creator A5060816750 @default.
• W2738798927 creator A5072463668 @default.
• W2738798927 creator A5076412210 @default.
• W2738798927 creator A5076532678 @default.
• W2738798927 creator A5078915747 @default.
• W2738798927 creator A5079160961 @default.
• W2738798927 creator A5083384676 @default.
• W2738798927 creator A5083475803 @default.
• W2738798927 creator A5084245554 @default.
• W2738798927 creator A5089532317 @default.
• W2738798927 date "2017-09-01" @default.
• W2738798927 modified "2023-10-15" @default.
• W2738798927 title "Molecular characterization of<i>Streptococcus pneumoniae</i>, particularly serotype19A/ST320, which emerged in Krasnoyarsk, Russia" @default.
• W2738798927 cites W1203026668 @default.
• W2738798927 cites W1439986590 @default.
• W2738798927 cites W1532986124 @default.
• W2738798927 cites W1564524022 @default.
• W2738798927 cites W1939568988 @default.
• W2738798927 cites W1954112402 @default.
• W2738798927 cites W1980193876 @default.
• W2738798927 cites W1983130542 @default.
• W2738798927 cites W1991549865 @default.
• W2738798927 cites W1999398338 @default.
• W2738798927 cites W1999742239 @default.
• W2738798927 cites W2001827876 @default.
• W2738798927 cites W2002459863 @default.
• W2738798927 cites W2008846329 @default.
• W2738798927 cites W2014197969 @default.
• W2738798927 cites W2039817895 @default.
• W2738798927 cites W2054051063 @default.
• W2738798927 cites W2054223680 @default.
• W2738798927 cites W2055905705 @default.
• W2738798927 cites W2055952697 @default.
• W2738798927 cites W2056400335 @default.
• W2738798927 cites W2059509103 @default.
• W2738798927 cites W2066496579 @default.
• W2738798927 cites W2067136681 @default.
• W2738798927 cites W2070398317 @default.
• W2738798927 cites W2074646866 @default.
• W2738798927 cites W2093093385 @default.
• W2738798927 cites W2097750123 @default.
• W2738798927 cites W2098788575 @default.
• W2738798927 cites W2104276786 @default.
• W2738798927 cites W2116160523 @default.
• W2738798927 cites W2117175264 @default.
• W2738798927 cites W2121535245 @default.
• W2738798927 cites W2124704072 @default.
• W2738798927 cites W2132081049 @default.
• W2738798927 cites W2133059828 @default.
• W2738798927 cites W2135152765 @default.
• W2738798927 cites W2135610044 @default.
• W2738798927 cites W2150500774 @default.
• W2738798927 cites W2152207030 @default.
• W2738798927 cites W2159553344 @default.
• W2738798927 cites W2160193310 @default.
• W2738798927 cites W2165475099 @default.
• W2738798927 cites W2168805867 @default.
• W2738798927 cites W2169729911 @default.
• W2738798927 cites W2195041459 @default.
• W2738798927 cites W2207495777 @default.
• W2738798927 cites W2264721366 @default.
• W2738798927 cites W2307873515 @default.
• W2738798927 cites W2308122722 @default.
• W2738798927 cites W2337436182 @default.
• W2738798927 cites W2341199367 @default.
• W2738798927 cites W2341947806 @default.
• W2738798927 cites W2517872601 @default.
• W2738798927 cites W4211042302 @default.
• W2738798927 cites W2093924178 @default.
• W2738798927 doi "https://doi.org/10.1111/1348-0421.12503" @default.
• W2738798927 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5639370" @default.
• W2738798927 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28736993" @default.
• W2738798927 hasPublicationYear "2017" @default.
• W2738798927 type Work @default.
• W2738798927 sameAs 2738798927 @default.
• W2738798927 citedByCount "3" @default.
• W2738798927 countsByYear W27387989272020 @default.
• W2738798927 countsByYear W27387989272021 @default.
• W2738798927 crossrefType "journal-article" @default.
• W2738798927 hasAuthorship W2738798927A5016679829 @default.
• W2738798927 hasAuthorship W2738798927A5023589163 @default.
• W2738798927 hasAuthorship W2738798927A5033858443 @default.
• W2738798927 hasAuthorship W2738798927A5034621712 @default.
• W2738798927 hasAuthorship W2738798927A5042762695 @default.
• W2738798927 hasAuthorship W2738798927A5052364651 @default.
• W2738798927 hasAuthorship W2738798927A5058422953 @default.
• W2738798927 hasAuthorship W2738798927A5060816750 @default.
• W2738798927 hasAuthorship W2738798927A5072463668 @default.
• W2738798927 hasAuthorship W2738798927A5076412210 @default.

• next