FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2738963630> ?p ?o ?g. }

• W2738963630 abstract "Introduction Follow up of Fontan patients involves a multimodality approach including imaging to assess cardiac function and cardiopulmonary exercise testing (CPET) to assess functional capacity. Decision making, including use of device therapy in conventional heart failure patients utilises predominantly structural information. We sought to assess whether cardiac structure as measured by conventional cardiac magnetic resonance parameters was related to functional capacity as assessed by CPET in a large Fontan cohort. Methods 233 Fontan patients under follow up were identified. Of these 76 patients had undergone a CMR and CPET within 12 months. The cohort was divided into 2 groups 1) 47 patients with either a lateral tunnel or total cavo-pulmonary connexion (TCPC group); mean age 19±4 years, 51% male and 2) 29 patients with an atriopulmonary Fontan (AP group); age 29±7 years, 48% male. Results There were no significance differences in imaging parameters between the 2 groups. The peak VO2 was significantly higher in the TCPC group (27±9 ml/kg/min) compared to the AP group (22±8 ml/kg/min, p 0.009) (Table 1). In the TCPC group only 19% of patients had a EF In the TPCP group the end diastolic volume (EDV), end systolic volume (ESV), stroke volume (SV) and ejection fraction (EF) did not correlate with the peak VO2, nor ventilatory product. Ventricular EF negatively correlated to NYHA class (r=−0.41, p 0.005) as did ventricular mass (r=−0.49, p 0.04). Rest partial pressure exhaled CO2 (rest PETCO2) correlated with the EDV (r=0.30, p 0.04) and SV (r=0.32, p 0.03). In the AP group there was no correlation either between EDV, ESV, SV and EF with VO2 peak or ventilatory product. Rest PETCO2 correlated with EDV (r=0.37, p 0.04), whilst rest O2 pulse correlated with SV (r=0.48, p 0.009) and ventricular mass (r=0.53, p 0.02). When determined for each functional class in the TCPC group there was no difference in EDV (p 0.75). Ventricular EF was different between NYHA Class: NYHA I (n=29) EF 64±8%, NYHA II (n=12) 55±7%, NYHA III (n=4) 63±7%, NYHA IV (n=1) 51%, P 0.005, but this did not represent a stepwise decline. In the AP group for each functional class there was no difference in EDV (p 0.1) or EF (p 0.6). The peak VO2 was different between functional classes for the TCPC and AP groups. The TCPC results were NYHA Class I 29±8; NYHA II 23±8; NYHA III 25±5; NYHA IV 11 p 0.03, whilst those for the AP group are NYHA I 25±7; NYHA II 19±7; NYHA III 16±5, (units ml/kg/min, p 0.006). Discussion This study demonstrates that no conventional cardiac remodelling parameters related to the patients functional capacity. Fontan patients may be disadvantaged when assessed for advanced heart failure strategies as ventricular EF is a poor marker of functional capacity in this cohort and a study assessing response based on exercise parameters may be warranted." @default.
• W2738963630 created "2017-07-31" @default.
• W2738963630 creator A5010791740 @default.
• W2738963630 creator A5015634964 @default.
• W2738963630 creator A5042295496 @default.
• W2738963630 creator A5045154993 @default.
• W2738963630 creator A5057865089 @default.
• W2738963630 creator A5061401731 @default.
• W2738963630 creator A5069573826 @default.
• W2738963630 creator A5072899043 @default.
• W2738963630 creator A5085274611 @default.
• W2738963630 date "2017-06-01" @default.
• W2738963630 modified "2023-09-23" @default.
• W2738963630 title "82 Relationship between cardiac structure and functional capacity in a fontan cohort" @default.
• W2738963630 doi "https://doi.org/10.1136/heartjnl-2017-311726.81" @default.
• W2738963630 hasPublicationYear "2017" @default.
• W2738963630 type Work @default.
• W2738963630 sameAs 2738963630 @default.
• W2738963630 citedByCount "0" @default.
• W2738963630 crossrefType "journal-article" @default.
• W2738963630 hasAuthorship W2738963630A5010791740 @default.
• W2738963630 hasAuthorship W2738963630A5015634964 @default.
• W2738963630 hasAuthorship W2738963630A5042295496 @default.
• W2738963630 hasAuthorship W2738963630A5045154993 @default.
• W2738963630 hasAuthorship W2738963630A5057865089 @default.
• W2738963630 hasAuthorship W2738963630A5061401731 @default.
• W2738963630 hasAuthorship W2738963630A5069573826 @default.
• W2738963630 hasAuthorship W2738963630A5072899043 @default.
• W2738963630 hasAuthorship W2738963630A5085274611 @default.
• W2738963630 hasBestOaLocation W27389636301 @default.
• W2738963630 hasConcept C126322002 @default.
• W2738963630 hasConcept C126838900 @default.
• W2738963630 hasConcept C139940330 @default.
• W2738963630 hasConcept C143409427 @default.
• W2738963630 hasConcept C164705383 @default.
• W2738963630 hasConcept C178853913 @default.
• W2738963630 hasConcept C21143770 @default.
• W2738963630 hasConcept C2776008845 @default.
• W2738963630 hasConcept C2776974648 @default.
• W2738963630 hasConcept C2778198053 @default.
• W2738963630 hasConcept C2780074459 @default.
• W2738963630 hasConcept C71924100 @default.
• W2738963630 hasConcept C72563966 @default.
• W2738963630 hasConcept C78085059 @default.
• W2738963630 hasConcept C80461066 @default.
• W2738963630 hasConceptScore W2738963630C126322002 @default.
• W2738963630 hasConceptScore W2738963630C126838900 @default.
• W2738963630 hasConceptScore W2738963630C139940330 @default.
• W2738963630 hasConceptScore W2738963630C143409427 @default.
• W2738963630 hasConceptScore W2738963630C164705383 @default.
• W2738963630 hasConceptScore W2738963630C178853913 @default.
• W2738963630 hasConceptScore W2738963630C21143770 @default.
• W2738963630 hasConceptScore W2738963630C2776008845 @default.
• W2738963630 hasConceptScore W2738963630C2776974648 @default.
• W2738963630 hasConceptScore W2738963630C2778198053 @default.
• W2738963630 hasConceptScore W2738963630C2780074459 @default.
• W2738963630 hasConceptScore W2738963630C71924100 @default.
• W2738963630 hasConceptScore W2738963630C72563966 @default.
• W2738963630 hasConceptScore W2738963630C78085059 @default.
• W2738963630 hasConceptScore W2738963630C80461066 @default.
• W2738963630 hasLocation W27389636301 @default.
• W2738963630 hasOpenAccess W2738963630 @default.
• W2738963630 hasPrimaryLocation W27389636301 @default.
• W2738963630 hasRelatedWork W2036374684 @default.
• W2738963630 hasRelatedWork W2067457183 @default.
• W2738963630 hasRelatedWork W2121932756 @default.
• W2738963630 hasRelatedWork W2149315632 @default.
• W2738963630 hasRelatedWork W2353571992 @default.
• W2738963630 hasRelatedWork W2356173303 @default.
• W2738963630 hasRelatedWork W2357920194 @default.
• W2738963630 hasRelatedWork W2358174411 @default.
• W2738963630 hasRelatedWork W2366118572 @default.
• W2738963630 hasRelatedWork W2367098177 @default.
• W2738963630 hasRelatedWork W2380049314 @default.
• W2738963630 hasRelatedWork W2390540930 @default.
• W2738963630 hasRelatedWork W2409116832 @default.
• W2738963630 hasRelatedWork W2410328159 @default.
• W2738963630 hasRelatedWork W2416091731 @default.
• W2738963630 hasRelatedWork W2766984427 @default.
• W2738963630 hasRelatedWork W3027405393 @default.
• W2738963630 hasRelatedWork W31267751 @default.
• W2738963630 hasRelatedWork W3147399374 @default.
• W2738963630 hasRelatedWork W3686367 @default.
• W2738963630 isParatext "false" @default.
• W2738963630 isRetracted "false" @default.
• W2738963630 magId "2738963630" @default.
• W2738963630 workType "article" @default.