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• W2739068957 abstract "OBJECTIVE: To compare the clinical profile in a Cameroonian cohort of patients with PD with an age, sex, PD duration-matched Spanish cohort with access to standard PD therapies (ELEP study cohort). BACKGROUND: Current data on the clinical profile of Parkinsons disease (PD) in sub-Saharan patients with limited and intermittent access to dopaminergic drugs are sparse. DESIGN/METHODS: Observational, cross-sectional design. Clinical and demographic data were collected using structured questionnaires and compared between the 2 groups. Disease and motor severity were assessed using the Hoehn and Yahr staging, SCOPA-Motor; autonomic features using the SCOPA-AUT; cognition using the SCOPA-Cognition; comorbidity using the Cumulative Illness Rating Scale-Geriatrics; psychosis using the modified Parkinson Psychosis Rating Scale; anxiety-depression using the Hospital Anxiety and Depression Scale; sleep using SCOPA-Sleep; psychosocial impairment using SCOPA-Psychosocial; pain and fatigue visual analogue scales, and patientsquality of life using EQ-5D. RESULTS: Seventy four patients with idiopathic PD were included (37 from each country) with a mean age of 64.4 + 10.5 years, 70.3% males, and mean disease duration of 5.6 + 5.9 years. Overall, Cameroonians were intermittently treated with antiparkinsonians drugs. Compared to the Spanish PD cohort, Cameroonians were on anticholinergics more frequently (p=0.005), dopaminergic agonists less frequently (p CONCLUSIONS: Limited and intermittent access to dopaminergic drugs have a dramatic negative impact on PD motor and non motor symptoms, and patientsquality of life. Supported by: Banca Civica Caja Burgos, UCB Company. Disclosure: Dr. Cubo Delgado has received personal compensation for activities with Abbott and UCB Pharma. Dr. Doumbe has nothing to disclose. Dr. Martinez-Martin has received personal compensation for activities with Novartis, Newron, Movement Disorders Society, and Solvay. Dr. Martinez-Martin has received research support from Novartis, Newron, and GlaxoSmithKline. Dr. Rodriguez-Blazquez has nothing to disclose. Dr. Kuate has nothing to disclose. Dr. Mariscal has nothing to disclose. Dr. Lopez has nothing to disclose. Dr. Catalan has nothing to disclose." @default.
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• W2739068957 date "2013-02-12" @default.
• W2739068957 modified "2023-10-18" @default.
• W2739068957 title "Parkinsons Disease Clinical Profile in Cameroon: A Comparison between Spanish and Cameroonian Cohorts (P03.066)" @default.
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