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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2739282015> ?p ?o ?g. }

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• W2739282015 abstract "Atypical teratoid/rhabdoid tumor (AT/RT) is a malignant tumor that is commonly associated with biallelic alterations of SMARCB1. Recurrent or refractory AT/RT has not been molecularly characterized as well. We present the case of a child with recurrent AT/RT who underwent clinically integrated molecular profiling (germline DNA and tumor DNA/RNA sequencing). This demonstrated a somatic lesion in CDKN1C alongside hallmark loss of SMARCB1. This data allowed us to explore potential personalized therapies for this patient and expose a molecular driver that may be involved in similar cases." @default.
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• W2739282015 date "2017-11-01" @default.
• W2739282015 modified "2023-09-27" @default.
• W2739282015 title "Loss of CDKN1C in a Recurrent Atypical Teratoid/Rhabdoid Tumor" @default.
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• W2739282015 doi "https://doi.org/10.1097/mph.0000000000000873" @default.
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