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• W2739421744 abstract "Background: Four direct oral anticoagulants (DOACs) have been approved for clinical use by many medicines regulatory agencies around the world. Due to increasing use of these drugs in routine practice, we planned an original study to investigate their worldwide diffusion using a popular Web-search engine. Methods: Two electronic searches were performed using Google Trends, the former using the keywords “warfarin” AND “heparin” AND “fondaparinux”, and the latter using the keywords “warfarin” AND “dabigatran” AND “rivaroxaban” AND “apixaban” AND “edoxaban”, both using the search criterion “prescription drug”. No language restriction was applied, and the searches were carried out from the first date available in Google Trends (January 1 st , 2004) to present time (June 1 st , 2017). Results: The median Google Trends score of warfarin (i.e., 86) was consistently higher than that of heparin (54; P Conclusions: The results of our analysis suggest that the popularity of DOACs is constantly increasing around the world, whereas that of warfarin has exhibited a constant and inexorable decline." @default.
• W2739421744 created "2017-07-31" @default.
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• W2739421744 date "2017-08-01" @default.
• W2739421744 modified "2023-10-10" @default.
• W2739421744 title "Direct oral anticoagulants: analysis of worldwide use and popularity using Google Trends" @default.
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• W2739421744 doi "https://doi.org/10.21037/atm.2017.06.65" @default.
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