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- W2739497053 abstract "Abstract Adaptive laboratory evolution (ALE) was employed to isolate arsenate and copper cross-resistant strains, from the copper-resistant M. sedula CuR1. The evolved strains, M. sedula ARS50-1 and M. sedula ARS50-2, contained 12 and 13 additional mutations, respectively, relative to M. sedula CuR1. Bioleaching capacity of a defined consortium (consisting of a naturally occurring strain and a genetically engineered copper sensitive strain) was increased by introduction of M. sedula ARS50-2, with 5.31 and 26.29% more copper recovered from enargite at a pulp density (PD) of 1 and 3% (w/v), respectively. M. sedula ARS50-2 arose as the predominant species and modulated the proportions of the other two strains after it had been introduced. Collectively, the higher Cu2+ resistance trait of M. sedula ARS50-2 resulted in a modulated microbial community structure, and consolidating enargite bioleaching especially at elevated PD." @default.
- W2739497053 created "2017-08-08" @default.
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- W2739497053 date "2017-12-01" @default.
- W2739497053 modified "2023-10-16" @default.
- W2739497053 title "Evolution of copper arsenate resistance for enhanced enargite bioleaching using the extreme thermoacidophile <i>Metallosphaera sedula</i>" @default.
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- W2739497053 doi "https://doi.org/10.1007/s10295-017-1973-5" @default.
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