FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2739768967> ?p ?o ?g. }

• W2739768967 abstract "Divergent synthesis of antimalarial troponoids, including naturally occurring compounds, some of which were identified and isolated by our group, has been achieved utilizing the total synthetic route of puberulic acid. Structure-activity relationships of natural products and simple troponoids inspired us to explore more detailed properties of this class of compounds. Access to new derivatives was facilitated through intermediate compounds generated during the total synthesis of puberulic acid by a stepwise oxidation-aromatization sequence to provide 7-hydroxytropolones and bromination for conversion of the carboxylic acid moiety. The first total synthesis of viticolin A, as well as the synthesis of different methyl-substituted derivatives, has also been achieved. In vitro antimalarial activity and cytotoxicity of novel derivatives were evaluated and fundamental information to facilitate the discovery of more promising antimalarials was obtained." @default.
• W2739768967 created "2017-08-08" @default.
• W2739768967 creator A5013040414 @default.
• W2739768967 creator A5034850441 @default.
• W2739768967 creator A5035775618 @default.
• W2739768967 creator A5038981388 @default.
• W2739768967 creator A5045164227 @default.
• W2739768967 creator A5050381773 @default.
• W2739768967 creator A5074937562 @default.
• W2739768967 creator A5078878264 @default.
• W2739768967 creator A5088787936 @default.
• W2739768967 date "2017-08-03" @default.
• W2739768967 modified "2023-10-18" @default.
• W2739768967 title "Antimalarial troponoids, puberulic acid and viticolins; divergent synthesis and structure-activity relationship studies" @default.
• W2739768967 cites W1983106841 @default.
• W2739768967 cites W1995253936 @default.
• W2739768967 cites W1999538365 @default.
• W2739768967 cites W2011631935 @default.
• W2739768967 cites W2012219614 @default.
• W2739768967 cites W2016812491 @default.
• W2739768967 cites W2031328960 @default.
• W2739768967 cites W2035530644 @default.
• W2739768967 cites W2045936441 @default.
• W2739768967 cites W2053791501 @default.
• W2739768967 cites W2062203105 @default.
• W2739768967 cites W2074583793 @default.
• W2739768967 cites W2086747526 @default.
• W2739768967 cites W2091229123 @default.
• W2739768967 cites W2120781318 @default.
• W2739768967 cites W2124249008 @default.
• W2739768967 cites W2131312936 @default.
• W2739768967 cites W2131896726 @default.
• W2739768967 cites W2135874703 @default.
• W2739768967 cites W2142726261 @default.
• W2739768967 cites W2144612995 @default.
• W2739768967 cites W2198907191 @default.
• W2739768967 cites W2234862336 @default.
• W2739768967 cites W2294626988 @default.
• W2739768967 cites W2296263363 @default.
• W2739768967 cites W2314927567 @default.
• W2739768967 cites W2400654452 @default.
• W2739768967 cites W262294882 @default.
• W2739768967 cites W2950421387 @default.
• W2739768967 cites W2952448758 @default.
• W2739768967 cites W4245831290 @default.
• W2739768967 cites W4293049708 @default.
• W2739768967 doi "https://doi.org/10.1038/s41598-017-07718-3" @default.
• W2739768967 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5543150" @default.
• W2739768967 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28775291" @default.
• W2739768967 hasPublicationYear "2017" @default.
• W2739768967 type Work @default.
• W2739768967 sameAs 2739768967 @default.
• W2739768967 citedByCount "11" @default.
• W2739768967 countsByYear W27397689672018 @default.
• W2739768967 countsByYear W27397689672019 @default.
• W2739768967 countsByYear W27397689672021 @default.
• W2739768967 countsByYear W27397689672022 @default.
• W2739768967 countsByYear W27397689672023 @default.
• W2739768967 crossrefType "journal-article" @default.
• W2739768967 hasAuthorship W2739768967A5013040414 @default.
• W2739768967 hasAuthorship W2739768967A5034850441 @default.
• W2739768967 hasAuthorship W2739768967A5035775618 @default.
• W2739768967 hasAuthorship W2739768967A5038981388 @default.
• W2739768967 hasAuthorship W2739768967A5045164227 @default.
• W2739768967 hasAuthorship W2739768967A5050381773 @default.
• W2739768967 hasAuthorship W2739768967A5074937562 @default.
• W2739768967 hasAuthorship W2739768967A5078878264 @default.
• W2739768967 hasAuthorship W2739768967A5088787936 @default.
• W2739768967 hasBestOaLocation W27397689671 @default.
• W2739768967 hasConcept C109316439 @default.
• W2739768967 hasConcept C161790260 @default.
• W2739768967 hasConcept C178790620 @default.
• W2739768967 hasConcept C185592680 @default.
• W2739768967 hasConcept C197865113 @default.
• W2739768967 hasConcept C202751555 @default.
• W2739768967 hasConcept C203014093 @default.
• W2739768967 hasConcept C21951064 @default.
• W2739768967 hasConcept C2776568683 @default.
• W2739768967 hasConcept C2778048844 @default.
• W2739768967 hasConcept C2778112365 @default.
• W2739768967 hasConcept C2778371730 @default.
• W2739768967 hasConcept C2779325354 @default.
• W2739768967 hasConcept C2908859342 @default.
• W2739768967 hasConcept C35753019 @default.
• W2739768967 hasConcept C55493867 @default.
• W2739768967 hasConcept C71240020 @default.
• W2739768967 hasConcept C86803240 @default.
• W2739768967 hasConceptScore W2739768967C109316439 @default.
• W2739768967 hasConceptScore W2739768967C161790260 @default.
• W2739768967 hasConceptScore W2739768967C178790620 @default.
• W2739768967 hasConceptScore W2739768967C185592680 @default.
• W2739768967 hasConceptScore W2739768967C197865113 @default.
• W2739768967 hasConceptScore W2739768967C202751555 @default.
• W2739768967 hasConceptScore W2739768967C203014093 @default.
• W2739768967 hasConceptScore W2739768967C21951064 @default.
• W2739768967 hasConceptScore W2739768967C2776568683 @default.
• W2739768967 hasConceptScore W2739768967C2778048844 @default.
• W2739768967 hasConceptScore W2739768967C2778112365 @default.
• W2739768967 hasConceptScore W2739768967C2778371730 @default.
• W2739768967 hasConceptScore W2739768967C2779325354 @default.

• next