FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2739899736> ?p ?o ?g. }

• W2739899736 endingPage "1548" @default.
• W2739899736 startingPage "1540" @default.
• W2739899736 abstract "Abstract Background: The higher risk of pancreatic cancer in Ashkenazi Jews compared with non-Jews is only partially explained by the increased frequency of BRCA1 and BRCA2 mutations in Ashkenazi Jews. Methods: We evaluated the impact of 16 established pancreatic cancer susceptibility loci in a case–control sample of American Jews, largely Ashkenazi, including 406 full-Jewish pancreatic cancer patients and 2,332 full-Jewish controls, genotyped as part of the Pancreatic Cancer Cohort and Case–Control Consortium I/II (PanScan I/II), Pancreatic Cancer Case-Control Consortium (PanC4), and Resource for Genetic Epidemiology Research on Adult Health and Aging (GERA) datasets. We compared risk in full-Jewish subjects with risk in part-Jewish; non-Jewish Southern European; and in the combined non-Jewish Eastern, Northern, Southern, and Western European (non-Jewish white European) subjects from the same datasets. Jewish ancestries were genetically identified using seeded Fast principal component analysis. Data were analyzed by unconditional logistic regression, and adjusted for age, sex, and principal components. Results: One SNP on chromosome 13q22.1 (rs9543325; OR, 1.36; 95% confidence interval, 1.16–1.58; P = 10−4.1) was significant in full-Jews. Individual ORs and minor allele frequencies were similar between Jewish and non-Jewish white European subjects. The average ORs across the 16 pancreatic cancer susceptibility loci for full-Jewish, full- plus part-Jewish, non-Jewish Southern European, and non-Jewish white European subjects were 1.25, 1.30, 1.31, and 1.26, respectively. Conclusions: The 16 pancreatic cancer susceptibility loci similarly impact Jewish and non-Jewish white European subjects, both individually and as summary odds. Impact: These 16 pancreatic cancer susceptibility loci likely do not explain the higher risk seen in Ashkenazi Jews. Cancer Epidemiol Biomarkers Prev; 26(10); 1540–8. ©2017 AACR." @default.
• W2739899736 created "2017-08-08" @default.
• W2739899736 creator A5006714908 @default.
• W2739899736 creator A5029218403 @default.
• W2739899736 creator A5039252809 @default.
• W2739899736 creator A5042493218 @default.
• W2739899736 creator A5055676175 @default.
• W2739899736 creator A5074828414 @default.
• W2739899736 creator A5076027451 @default.
• W2739899736 date "2017-10-01" @default.
• W2739899736 modified "2023-09-27" @default.
• W2739899736 title "Impact of Sixteen Established Pancreatic Cancer Susceptibility Loci in American Jews" @default.
• W2739899736 cites W1534877200 @default.
• W2739899736 cites W156257350 @default.
• W2739899736 cites W1757407923 @default.
• W2739899736 cites W178358174 @default.
• W2739899736 cites W1964874633 @default.
• W2739899736 cites W1973234126 @default.
• W2739899736 cites W2003865797 @default.
• W2739899736 cites W2006071863 @default.
• W2739899736 cites W2006478411 @default.
• W2739899736 cites W2018270561 @default.
• W2739899736 cites W2021701419 @default.
• W2739899736 cites W2045658286 @default.
• W2739899736 cites W2078675213 @default.
• W2739899736 cites W2083870677 @default.
• W2739899736 cites W2087036932 @default.
• W2739899736 cites W2092188706 @default.
• W2739899736 cites W2092590432 @default.
• W2739899736 cites W2093365882 @default.
• W2739899736 cites W2096779733 @default.
• W2739899736 cites W2096791516 @default.
• W2739899736 cites W2099085143 @default.
• W2739899736 cites W2099192810 @default.
• W2739899736 cites W2102413929 @default.
• W2739899736 cites W2121625711 @default.
• W2739899736 cites W2132073122 @default.
• W2739899736 cites W2140126911 @default.
• W2739899736 cites W2146731218 @default.
• W2739899736 cites W2157752701 @default.
• W2739899736 cites W2161036476 @default.
• W2739899736 cites W2169862738 @default.
• W2739899736 cites W2170044093 @default.
• W2739899736 cites W2170552969 @default.
• W2739899736 cites W2171653205 @default.
• W2739899736 cites W2176686025 @default.
• W2739899736 cites W2215458091 @default.
• W2739899736 cites W2216458865 @default.
• W2739899736 cites W2265537752 @default.
• W2739899736 cites W2275814392 @default.
• W2739899736 cites W2284253967 @default.
• W2739899736 cites W2319794291 @default.
• W2739899736 cites W2437225478 @default.
• W2739899736 cites W2461173510 @default.
• W2739899736 cites W2509403461 @default.
• W2739899736 cites W92435828 @default.
• W2739899736 doi "https://doi.org/10.1158/1055-9965.epi-17-0262" @default.
• W2739899736 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5626623" @default.
• W2739899736 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28754795" @default.
• W2739899736 hasPublicationYear "2017" @default.
• W2739899736 type Work @default.
• W2739899736 sameAs 2739899736 @default.
• W2739899736 citedByCount "6" @default.
• W2739899736 countsByYear W27398997362018 @default.
• W2739899736 countsByYear W27398997362020 @default.
• W2739899736 countsByYear W27398997362021 @default.
• W2739899736 countsByYear W27398997362022 @default.
• W2739899736 crossrefType "journal-article" @default.
• W2739899736 hasAuthorship W2739899736A5006714908 @default.
• W2739899736 hasAuthorship W2739899736A5029218403 @default.
• W2739899736 hasAuthorship W2739899736A5039252809 @default.
• W2739899736 hasAuthorship W2739899736A5042493218 @default.
• W2739899736 hasAuthorship W2739899736A5055676175 @default.
• W2739899736 hasAuthorship W2739899736A5074828414 @default.
• W2739899736 hasAuthorship W2739899736A5076027451 @default.
• W2739899736 hasBestOaLocation W27398997361 @default.
• W2739899736 hasConcept C121608353 @default.
• W2739899736 hasConcept C126322002 @default.
• W2739899736 hasConcept C143998085 @default.
• W2739899736 hasConcept C144024400 @default.
• W2739899736 hasConcept C149923435 @default.
• W2739899736 hasConcept C150152722 @default.
• W2739899736 hasConcept C166957645 @default.
• W2739899736 hasConcept C2780210213 @default.
• W2739899736 hasConcept C54355233 @default.
• W2739899736 hasConcept C71924100 @default.
• W2739899736 hasConcept C86803240 @default.
• W2739899736 hasConcept C95457728 @default.
• W2739899736 hasConceptScore W2739899736C121608353 @default.
• W2739899736 hasConceptScore W2739899736C126322002 @default.
• W2739899736 hasConceptScore W2739899736C143998085 @default.
• W2739899736 hasConceptScore W2739899736C144024400 @default.
• W2739899736 hasConceptScore W2739899736C149923435 @default.
• W2739899736 hasConceptScore W2739899736C150152722 @default.
• W2739899736 hasConceptScore W2739899736C166957645 @default.
• W2739899736 hasConceptScore W2739899736C2780210213 @default.
• W2739899736 hasConceptScore W2739899736C54355233 @default.
• W2739899736 hasConceptScore W2739899736C71924100 @default.

• next