Matches in SemOpenAlex for { <https://semopenalex.org/work/W2739989798> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2739989798 abstract "Irradiation (IR) has become more important and effective therapeutic approach for cancer in chest (lung, breast and esophagus), however, IR-induced pneumonitis/fibrosis is still the bottle-neck for using higher IR dose to more effectively eradicate cancer cells, since there is no drug to treat the companion IR-injury toxicity. Glycyrrhizic Acid (GLA) has been used to treat hepatitis and liver fibrosis for almost 3 decades in Asia. It has no lethal dose in animal and no obvious side effect in human, which allows for 2 to 3 months use to imitate chronic fibrosis. Here we report for the first time that while GLA was used to treat the liver damage caused by chemotherapy, it presented a surprising mitigation effect on a 2nd round IR treatment-induced severe lung injury in a recurrent stage B (T2N3M0) lung cancer patient who had severe pneumonitis during the 1st round IR therapy. Combined with the fact that GLA effectively mitigates IR induced pneumonitis/fibrosis in animal model, we conclude that GLA is a potential good candidate to be developed as anti-IR lung injury drug." @default.
- W2739989798 created "2017-08-08" @default.
- W2739989798 creator A5008573060 @default.
- W2739989798 creator A5034715063 @default.
- W2739989798 creator A5036457690 @default.
- W2739989798 creator A5042135724 @default.
- W2739989798 creator A5051894582 @default.
- W2739989798 date "2017-01-01" @default.
- W2739989798 modified "2023-09-23" @default.
- W2739989798 title "Glycyrrhizic Acid Mitigates 2nd Round Radiotherapy-Induced Severe Lung Injury: A Case Report" @default.
- W2739989798 doi "https://doi.org/10.4172/2472-1018.1000125" @default.
- W2739989798 hasPublicationYear "2017" @default.
- W2739989798 type Work @default.
- W2739989798 sameAs 2739989798 @default.
- W2739989798 citedByCount "1" @default.
- W2739989798 countsByYear W27399897982021 @default.
- W2739989798 crossrefType "journal-article" @default.
- W2739989798 hasAuthorship W2739989798A5008573060 @default.
- W2739989798 hasAuthorship W2739989798A5034715063 @default.
- W2739989798 hasAuthorship W2739989798A5036457690 @default.
- W2739989798 hasAuthorship W2739989798A5042135724 @default.
- W2739989798 hasAuthorship W2739989798A5051894582 @default.
- W2739989798 hasBestOaLocation W27399897981 @default.
- W2739989798 hasConcept C121608353 @default.
- W2739989798 hasConcept C126322002 @default.
- W2739989798 hasConcept C142724271 @default.
- W2739989798 hasConcept C143998085 @default.
- W2739989798 hasConcept C2776256026 @default.
- W2739989798 hasConcept C2776637226 @default.
- W2739989798 hasConcept C2777714996 @default.
- W2739989798 hasConcept C2777819096 @default.
- W2739989798 hasConcept C2779524853 @default.
- W2739989798 hasConcept C2780559512 @default.
- W2739989798 hasConcept C2781244666 @default.
- W2739989798 hasConcept C502942594 @default.
- W2739989798 hasConcept C509974204 @default.
- W2739989798 hasConcept C71924100 @default.
- W2739989798 hasConcept C90924648 @default.
- W2739989798 hasConceptScore W2739989798C121608353 @default.
- W2739989798 hasConceptScore W2739989798C126322002 @default.
- W2739989798 hasConceptScore W2739989798C142724271 @default.
- W2739989798 hasConceptScore W2739989798C143998085 @default.
- W2739989798 hasConceptScore W2739989798C2776256026 @default.
- W2739989798 hasConceptScore W2739989798C2776637226 @default.
- W2739989798 hasConceptScore W2739989798C2777714996 @default.
- W2739989798 hasConceptScore W2739989798C2777819096 @default.
- W2739989798 hasConceptScore W2739989798C2779524853 @default.
- W2739989798 hasConceptScore W2739989798C2780559512 @default.
- W2739989798 hasConceptScore W2739989798C2781244666 @default.
- W2739989798 hasConceptScore W2739989798C502942594 @default.
- W2739989798 hasConceptScore W2739989798C509974204 @default.
- W2739989798 hasConceptScore W2739989798C71924100 @default.
- W2739989798 hasConceptScore W2739989798C90924648 @default.
- W2739989798 hasLocation W27399897981 @default.
- W2739989798 hasOpenAccess W2739989798 @default.
- W2739989798 hasPrimaryLocation W27399897981 @default.
- W2739989798 hasRelatedWork W149718172 @default.
- W2739989798 hasRelatedWork W2048188284 @default.
- W2739989798 hasRelatedWork W2079244145 @default.
- W2739989798 hasRelatedWork W2086498668 @default.
- W2739989798 hasRelatedWork W2097228651 @default.
- W2739989798 hasRelatedWork W2103727897 @default.
- W2739989798 hasRelatedWork W2108682296 @default.
- W2739989798 hasRelatedWork W2161226032 @default.
- W2739989798 hasRelatedWork W2161654376 @default.
- W2739989798 hasRelatedWork W2161874065 @default.
- W2739989798 hasRelatedWork W2185233414 @default.
- W2739989798 hasRelatedWork W2318167696 @default.
- W2739989798 hasRelatedWork W2486502284 @default.
- W2739989798 hasRelatedWork W2751529676 @default.
- W2739989798 hasRelatedWork W2791659939 @default.
- W2739989798 hasRelatedWork W2791851098 @default.
- W2739989798 hasRelatedWork W3134908815 @default.
- W2739989798 hasRelatedWork W3192115369 @default.
- W2739989798 hasRelatedWork W91859960 @default.
- W2739989798 isParatext "false" @default.
- W2739989798 isRetracted "false" @default.
- W2739989798 magId "2739989798" @default.
- W2739989798 workType "article" @default.