FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2740005909> ?p ?o ?g. }

• W2740005909 endingPage "32" @default.
• W2740005909 startingPage "25" @default.
• W2740005909 abstract "Nucleotide-binding oligomerization domain (NOD)-like receptors or NOD-like receptors (NLRs) have been implicated in several disease pathologies associated with inflammation. Since local and systemic inflammation is a hallmark of both term and preterm labour, a role for NLRs at the materno-fetal interface has been postulated. Gene expression and immunolocalisation of NLR family members in human placenta, choriodecidua, and amnion were examined. Tissue explants were used to examine the response to activators of NOD1 (Tri-DAP), NOD2 (MDP) and NLRP3 (nigericin). Cell/tissue-free supernatants were examined for the production of interleukin (IL)-1β, IL-6, IL-8 and IL-10 using specific ELISAs. Expression of transcripts for NOD1, NOD2, NLRP3, NLRC4, NLRX1, NLRP1 and NAIP and protein expression of NOD1, NOD2 and NLRP3 were a broad feature of all term gestation-associated tissues. Production of cytokines was increased significantly in response to all ligands in placenta and choriodecidua, except for MDP-induced IL-10. Similarly, there was a significant in the amnion except for MDP induced IL-1β and IL-10 response to either agonist. IL-1β production was dependent on caspase-1 regardless of agonist used or tissue examined. Term human gestation-associated tissues express functional NLRs which likely play a role in both sterile and pathogen-driven inflammatory responses at the materno-fetal interface." @default.
• W2740005909 created "2017-08-08" @default.
• W2740005909 creator A5000498716 @default.
• W2740005909 creator A5015494439 @default.
• W2740005909 creator A5026117707 @default.
• W2740005909 creator A5049858481 @default.
• W2740005909 creator A5057332050 @default.
• W2740005909 creator A5059129138 @default.
• W2740005909 date "2017-10-01" @default.
• W2740005909 modified "2023-09-30" @default.
• W2740005909 title "Expression and function of NOD-like receptors by human term gestation-associated tissues" @default.
• W2740005909 cites W1559677484 @default.
• W2740005909 cites W1561041814 @default.
• W2740005909 cites W1564315843 @default.
• W2740005909 cites W1594875017 @default.
• W2740005909 cites W1595106840 @default.
• W2740005909 cites W1886716828 @default.
• W2740005909 cites W1982745955 @default.
• W2740005909 cites W2005410446 @default.
• W2740005909 cites W2014975671 @default.
• W2740005909 cites W2015449243 @default.
• W2740005909 cites W2022887856 @default.
• W2740005909 cites W2024562235 @default.
• W2740005909 cites W2025092283 @default.
• W2740005909 cites W2039321774 @default.
• W2740005909 cites W2045560520 @default.
• W2740005909 cites W2054625009 @default.
• W2740005909 cites W2056666667 @default.
• W2740005909 cites W2063007222 @default.
• W2740005909 cites W2071032971 @default.
• W2740005909 cites W2077861814 @default.
• W2740005909 cites W2085213100 @default.
• W2740005909 cites W2096298138 @default.
• W2740005909 cites W2115763109 @default.
• W2740005909 cites W2116851732 @default.
• W2740005909 cites W2130714174 @default.
• W2740005909 cites W2141924517 @default.
• W2740005909 cites W2149222281 @default.
• W2740005909 cites W2150702412 @default.
• W2740005909 cites W2155932634 @default.
• W2740005909 cites W2160784315 @default.
• W2740005909 cites W2164197794 @default.
• W2740005909 cites W2186434418 @default.
• W2740005909 cites W2196329331 @default.
• W2740005909 cites W2196530082 @default.
• W2740005909 cites W2232127504 @default.
• W2740005909 cites W2558807950 @default.
• W2740005909 cites W2567945295 @default.
• W2740005909 cites W2588109905 @default.
• W2740005909 cites W2736176055 @default.
• W2740005909 doi "https://doi.org/10.1016/j.placenta.2017.07.017" @default.
• W2740005909 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28962692" @default.
• W2740005909 hasPublicationYear "2017" @default.
• W2740005909 type Work @default.
• W2740005909 sameAs 2740005909 @default.
• W2740005909 citedByCount "17" @default.
• W2740005909 countsByYear W27400059092018 @default.
• W2740005909 countsByYear W27400059092019 @default.
• W2740005909 countsByYear W27400059092020 @default.
• W2740005909 countsByYear W27400059092021 @default.
• W2740005909 countsByYear W27400059092022 @default.
• W2740005909 countsByYear W27400059092023 @default.
• W2740005909 crossrefType "journal-article" @default.
• W2740005909 hasAuthorship W2740005909A5000498716 @default.
• W2740005909 hasAuthorship W2740005909A5015494439 @default.
• W2740005909 hasAuthorship W2740005909A5026117707 @default.
• W2740005909 hasAuthorship W2740005909A5049858481 @default.
• W2740005909 hasAuthorship W2740005909A5057332050 @default.
• W2740005909 hasAuthorship W2740005909A5059129138 @default.
• W2740005909 hasBestOaLocation W27400059092 @default.
• W2740005909 hasConcept C134018914 @default.
• W2740005909 hasConcept C136449434 @default.
• W2740005909 hasConcept C170493617 @default.
• W2740005909 hasConcept C172680121 @default.
• W2740005909 hasConcept C203014093 @default.
• W2740005909 hasConcept C2776914184 @default.
• W2740005909 hasConcept C2776953305 @default.
• W2740005909 hasConcept C2777209026 @default.
• W2740005909 hasConcept C2777291061 @default.
• W2740005909 hasConcept C2779234561 @default.
• W2740005909 hasConcept C2780646683 @default.
• W2740005909 hasConcept C54355233 @default.
• W2740005909 hasConcept C55493867 @default.
• W2740005909 hasConcept C555293320 @default.
• W2740005909 hasConcept C55851684 @default.
• W2740005909 hasConcept C7573103 @default.
• W2740005909 hasConcept C86803240 @default.
• W2740005909 hasConcept C95444343 @default.
• W2740005909 hasConceptScore W2740005909C134018914 @default.
• W2740005909 hasConceptScore W2740005909C136449434 @default.
• W2740005909 hasConceptScore W2740005909C170493617 @default.
• W2740005909 hasConceptScore W2740005909C172680121 @default.
• W2740005909 hasConceptScore W2740005909C203014093 @default.
• W2740005909 hasConceptScore W2740005909C2776914184 @default.
• W2740005909 hasConceptScore W2740005909C2776953305 @default.
• W2740005909 hasConceptScore W2740005909C2777209026 @default.
• W2740005909 hasConceptScore W2740005909C2777291061 @default.
• W2740005909 hasConceptScore W2740005909C2779234561 @default.

• next