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- W2740178847 abstract "Objective: To determine the in vitro antimicrobial activity of probiotic containing milk against community acquired bacterial pathogens in the pediatric age group. Design : Experimental Study Methods: In vitro analysis of the antimicrobial activity of probiotic milk in comparison to antibiotics against control strains based on the Kirby Bauer Method of disc susceptibility testing. Kruskall Wallis Test was used to analyze the difference between the mean zones of inhibition of the different control groups. Chi square and Fisher Exact Test was used to analyze % susceptibility. Results: Zones of inhibition of probiotic containing milk were observed among the three bacterial pathogens tested. The mean zones of inhibition produced by the probiotic milk showed smaller means for Streptococcus pneumoniae ( 9.04 +/-5.26) and H. influenzae (9.76 +/ - 7.65) as compared to their respective antibiotics: Penicillin G (30.18+/-0.70) and Chloramphenicol (30.96 +/- 1.86) (p value <0.000001). A larger mean zone of inhibition was produced for Staphyloccocus aureus (16.96+/- 5.30) compared to Oxacillin (12.92+/- 0.65). Comparison of the % susceptibility showed higher susceptibility of Streptococcus pneumoniae to Penicillin G and H. influenzae to Chloramphenicol when compared to the probiotic containing milk. Staphyloccocus aureus however, showed a better susceptibility to the probiotic containing milk (88%) vs. Oxacillin (64%) with a P value of 0.04. Conclusion: Probiotic milk containing Lactobacillus and Bifidobacteria was observed to have in vitro antimicrobial activity against Streptococcus pneumoniae, H. influenzae, and Staphyloccocus aureus . It has a better antimicrobial activity against S. aureus as demonstrated by a larger zone of inhibition and increased proportion of disc susceptibility than Oxacillin." @default.
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- W2740178847 date "2005-01-01" @default.
- W2740178847 modified "2023-09-27" @default.
- W2740178847 title "IN VITRO STUDY ON THE ANTIMICROBIAL ACTIVITY OF PROBIOTIC MILK AGAINST COMMON PEDIATRIC COMMUNITY ACQUIRED RES- PIRATORY PATHOGENS" @default.
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