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- W2740244937 abstract "ABSTRACT Pulmonaryneuroendocrinecells, identified bytheir positive immunochemical reaction for neurone specific enolase, were readily demonstrable and uniformly distributed in 15 pairs ofnormaladult humanlungs. About65%contained gastrin releasing peptide andnearly all the rest containedcalcitonin. Leucine-enkephalin was not found. Serotonincontainingcells were few, andcells immunoreactivefor adrenocorticotrophin andantidiuretichormone were absent. About one in 10 cells was argyrophilic, and costorage ofpeptides was not seen. IntroductionPulmonary neuroendocrine cells in normal subjectsare thought to contain the three peptides calcitonin,'gastrin releasing peptide (the mammalian analogue ofbombesin),2 and leucine-enkephalin,3 andtheamine 5-hydroxytryptamine (5-HT; serotonin).4 These cellsmaybe solitary5 or form clusters,6 which are termed neuroepithelial bodies7ifinnervated. Becauseoftheir sparsity and lack ofquantitative data on their distri- bution, and because many different methods" @default.
- W2740244937 created "2017-08-08" @default.
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- W2740244937 date "2011-01-01" @default.
- W2740244937 modified "2023-09-23" @default.
- W2740244937 title "Neuroendocrine cell populations innormal human lungs: aquantitative study" @default.
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