Matches in SemOpenAlex for { <https://semopenalex.org/work/W2740258566> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2740258566 endingPage "e0182108" @default.
- W2740258566 startingPage "e0182108" @default.
- W2740258566 abstract "Background India ink microscopy on cerebrospinal fluid is still utilized in resource limited settings for the diagnosis of cryptococcal meningitis despite its poor sensitivity. We hypothesized that staining fungal nucleic acids with fluorescent dyes instead of the capsule with India ink might improve sensitivity for the diagnosis of cryptococcal meningitis. Methods We enrolled 96 HIV-infected participants with cryptococcal meningitis who provided 194 CSF specimens at serial time points in Kampala, Uganda. Cryptococcosis was diagnosed by cerebrospinal fluid (CSF) cryptococcal antigen (CrAg) test and only positive samples were included. We stained CSF with India ink and acridine orange. We cultured the same samples on standard fungal media. We compared acridine orange to CrAg, India ink and CSF culture. Results Acridine orange was more sensitive (96%) than India ink (79%) with reference to CSF CrAg. Acridine orange and India ink had a statistically significant difference (P<0.001) with a 25% correlation for detection of Cryptococcus yeasts. India ink had more negative results (22%) than acridine orange (4%). The sensitivity for India ink increased (86%) while that of acridine orange did not change (97%) when compared to CSF culture. However, both India ink and acridine orange had poor predictive values with reference to culture. Conclusion Acridine orange is a better alternative to India ink in the rapid detection of cryptococcosis among CrAg positive HIV patients." @default.
- W2740258566 created "2017-08-08" @default.
- W2740258566 creator A5027410574 @default.
- W2740258566 creator A5035126929 @default.
- W2740258566 creator A5035384197 @default.
- W2740258566 creator A5064975634 @default.
- W2740258566 creator A5090135039 @default.
- W2740258566 date "2017-07-27" @default.
- W2740258566 modified "2023-10-12" @default.
- W2740258566 title "Acridine orange fluorescent microscopy is more sensitive than India ink light microscopy in the rapid detection of cryptococcosis among CrAg positive HIV patients" @default.
- W2740258566 cites W1950009220 @default.
- W2740258566 cites W1976256249 @default.
- W2740258566 cites W1992677251 @default.
- W2740258566 cites W2050108097 @default.
- W2740258566 cites W2068282303 @default.
- W2740258566 cites W2075114517 @default.
- W2740258566 cites W2075277346 @default.
- W2740258566 cites W2079513681 @default.
- W2740258566 cites W2154894130 @default.
- W2740258566 cites W2158404712 @default.
- W2740258566 cites W2164278547 @default.
- W2740258566 cites W2334206563 @default.
- W2740258566 cites W4233381066 @default.
- W2740258566 doi "https://doi.org/10.1371/journal.pone.0182108" @default.
- W2740258566 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5531523" @default.
- W2740258566 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28750078" @default.
- W2740258566 hasPublicationYear "2017" @default.
- W2740258566 type Work @default.
- W2740258566 sameAs 2740258566 @default.
- W2740258566 citedByCount "11" @default.
- W2740258566 countsByYear W27402585662017 @default.
- W2740258566 countsByYear W27402585662019 @default.
- W2740258566 countsByYear W27402585662020 @default.
- W2740258566 countsByYear W27402585662021 @default.
- W2740258566 countsByYear W27402585662022 @default.
- W2740258566 countsByYear W27402585662023 @default.
- W2740258566 crossrefType "journal-article" @default.
- W2740258566 hasAuthorship W2740258566A5027410574 @default.
- W2740258566 hasAuthorship W2740258566A5035126929 @default.
- W2740258566 hasAuthorship W2740258566A5035384197 @default.
- W2740258566 hasAuthorship W2740258566A5064975634 @default.
- W2740258566 hasAuthorship W2740258566A5090135039 @default.
- W2740258566 hasBestOaLocation W27402585661 @default.
- W2740258566 hasConcept C105702510 @default.
- W2740258566 hasConcept C141071460 @default.
- W2740258566 hasConcept C142724271 @default.
- W2740258566 hasConcept C18823058 @default.
- W2740258566 hasConcept C2776924795 @default.
- W2740258566 hasConcept C2779102032 @default.
- W2740258566 hasConcept C2779413141 @default.
- W2740258566 hasConcept C2781026528 @default.
- W2740258566 hasConcept C2994403803 @default.
- W2740258566 hasConcept C31903555 @default.
- W2740258566 hasConcept C54355233 @default.
- W2740258566 hasConcept C71924100 @default.
- W2740258566 hasConcept C74864618 @default.
- W2740258566 hasConcept C83082669 @default.
- W2740258566 hasConcept C86803240 @default.
- W2740258566 hasConceptScore W2740258566C105702510 @default.
- W2740258566 hasConceptScore W2740258566C141071460 @default.
- W2740258566 hasConceptScore W2740258566C142724271 @default.
- W2740258566 hasConceptScore W2740258566C18823058 @default.
- W2740258566 hasConceptScore W2740258566C2776924795 @default.
- W2740258566 hasConceptScore W2740258566C2779102032 @default.
- W2740258566 hasConceptScore W2740258566C2779413141 @default.
- W2740258566 hasConceptScore W2740258566C2781026528 @default.
- W2740258566 hasConceptScore W2740258566C2994403803 @default.
- W2740258566 hasConceptScore W2740258566C31903555 @default.
- W2740258566 hasConceptScore W2740258566C54355233 @default.
- W2740258566 hasConceptScore W2740258566C71924100 @default.
- W2740258566 hasConceptScore W2740258566C74864618 @default.
- W2740258566 hasConceptScore W2740258566C83082669 @default.
- W2740258566 hasConceptScore W2740258566C86803240 @default.
- W2740258566 hasFunder F4320322921 @default.
- W2740258566 hasFunder F4320332161 @default.
- W2740258566 hasFunder F4320334626 @default.
- W2740258566 hasIssue "7" @default.
- W2740258566 hasLocation W27402585661 @default.
- W2740258566 hasLocation W27402585662 @default.
- W2740258566 hasLocation W27402585663 @default.
- W2740258566 hasLocation W27402585664 @default.
- W2740258566 hasOpenAccess W2740258566 @default.
- W2740258566 hasPrimaryLocation W27402585661 @default.
- W2740258566 hasRelatedWork W2001297259 @default.
- W2740258566 hasRelatedWork W2029528444 @default.
- W2740258566 hasRelatedWork W2335349522 @default.
- W2740258566 hasRelatedWork W2396041707 @default.
- W2740258566 hasRelatedWork W2413422450 @default.
- W2740258566 hasRelatedWork W2416433882 @default.
- W2740258566 hasRelatedWork W2559706950 @default.
- W2740258566 hasRelatedWork W4230908556 @default.
- W2740258566 hasRelatedWork W4313829270 @default.
- W2740258566 hasRelatedWork W2774493415 @default.
- W2740258566 hasVolume "12" @default.
- W2740258566 isParatext "false" @default.
- W2740258566 isRetracted "false" @default.
- W2740258566 magId "2740258566" @default.
- W2740258566 workType "article" @default.