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• W2740564621 startingPage "20170254" @default.
• W2740564621 abstract "In molluscs, two homeobox genes, engrailed ( en ) and distal-less ( dlx ), are transcription factors that are expressed in correlation with shell development. They are expressed in the regions between shell-forming and non-shell-forming cells, likely defining the boundaries of shell-forming fields. Here we investigate the expression of two transcription factors in the brachiopod Lingula anatina . We find that en is expressed in larval mantle lobes, whereas dlx is expressed in larval tentacles. We also demonstrate that the embryonic shell marker mantle peroxidase ( mpox ) is specifically expressed in mantle lobes. Our results suggest that en and mpox are possibly involved in brachiopod embryonic shell development. We discuss the evolutionary developmental origin of lophotrochozoan biomineralization through independent gene co-option." @default.
• W2740564621 created "2017-08-08" @default.
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• W2740564621 date "2017-08-01" @default.
• W2740564621 modified "2023-10-02" @default.
• W2740564621 title "Possible co-option of<i>engrailed</i>during brachiopod and mollusc shell development" @default.
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• W2740564621 doi "https://doi.org/10.1098/rsbl.2017.0254" @default.
• W2740564621 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5582104" @default.
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