FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2740806938> ?p ?o ?g. }

• W2740806938 abstract "Objective: The study was conducted to examine the effects of Galangin(GA), a natural flavonoid of the rhizome Alpinia galanga on the levels of inflammatory markers caspase-1, IL-1β, IL-18 and antioxidant status in rats subjected to experimental pancreatitis by ethanol(EtOH) and cerulein administration. Methods: For the study, adult male albino Wistar rats were divided into four groups. Group 1 and 2 served as control and received normal diet for 5 weeks. Group 3 and 4 received an isocaloric diet , ethanol 8-12 g/ kg body weight/day and also 20µg/kg body wt. of cerulein intraperitonially for the last 3 weeks of the experimental period. In addition, group 2 and 4 were administered 100µg/kg body wt. of galangin orally by intragastric intubation for the last 3 weeks of the experimental period. Serum lipase, amylase, caspase-1, IL-1β, IL-18, thiobarbituric acid reacting substances(TBARS) and antioxidant status were assessed. Results: A significant increase in the levels of serum lipase/amylase ratio, caspase-1 activity, IL-1β, IL-18 and TBARS were observed in ethanolcerulein treated rats compared to those co-administered with galangin. Galangin supplementation along with ethanol-cerulein treatment significantly maintained the levels of antioxidants catalase, superoxide dismutase, glutathione peroxidase and reduced the oxidative stress in group 4 animals. Conclusion: The caspase-1 inhibitory activity of galangin is well evidenced from the study which may be due to its modulating effect either on caspase-1 synthesis or on activation of procaspase-1 . Also the observations suggest that the anti-inflammatory activity of galangin may be attributed to its antioxidant property of scavenging the free radicals which aggravate the process of inflammation." @default.
• W2740806938 created "2017-08-08" @default.
• W2740806938 creator A5046909769 @default.
• W2740806938 creator A5049846038 @default.
• W2740806938 creator A5081819370 @default.
• W2740806938 date "2013-01-01" @default.
• W2740806938 modified "2023-09-26" @default.
• W2740806938 title "EFFECT OF GALANGIN ON ETHANOL AND CERULEIN INDUCED INFLAMMATORY CHANGES IN PANCREAS: A BIOCHEMICAL STUDY IN RAT MODEL" @default.
• W2740806938 cites W1518143481 @default.
• W2740806938 cites W1538399032 @default.
• W2740806938 cites W1544880192 @default.
• W2740806938 cites W1546592314 @default.
• W2740806938 cites W1599342152 @default.
• W2740806938 cites W1827922241 @default.
• W2740806938 cites W1964542062 @default.
• W2740806938 cites W1967002916 @default.
• W2740806938 cites W1969281151 @default.
• W2740806938 cites W1973351162 @default.
• W2740806938 cites W1975032025 @default.
• W2740806938 cites W1984338631 @default.
• W2740806938 cites W1993164825 @default.
• W2740806938 cites W1999688501 @default.
• W2740806938 cites W2016490655 @default.
• W2740806938 cites W2031753589 @default.
• W2740806938 cites W2039477840 @default.
• W2740806938 cites W2051658957 @default.
• W2740806938 cites W2054260525 @default.
• W2740806938 cites W2059945363 @default.
• W2740806938 cites W2064412092 @default.
• W2740806938 cites W2088287674 @default.
• W2740806938 cites W2115898270 @default.
• W2740806938 cites W2126811226 @default.
• W2740806938 cites W2128635872 @default.
• W2740806938 cites W2139648891 @default.
• W2740806938 cites W2141449020 @default.
• W2740806938 cites W2147141683 @default.
• W2740806938 cites W2153029682 @default.
• W2740806938 cites W2156351918 @default.
• W2740806938 cites W2167447447 @default.
• W2740806938 cites W2374896348 @default.
• W2740806938 cites W2410337980 @default.
• W2740806938 cites W2412892956 @default.
• W2740806938 cites W2600521889 @default.
• W2740806938 cites W77084047 @default.
• W2740806938 cites W2188377169 @default.
• W2740806938 hasPublicationYear "2013" @default.
• W2740806938 type Work @default.
• W2740806938 sameAs 2740806938 @default.
• W2740806938 citedByCount "0" @default.
• W2740806938 crossrefType "journal-article" @default.
• W2740806938 hasAuthorship W2740806938A5046909769 @default.
• W2740806938 hasAuthorship W2740806938A5049846038 @default.
• W2740806938 hasAuthorship W2740806938A5081819370 @default.
• W2740806938 hasConcept C126322002 @default.
• W2740806938 hasConcept C134018914 @default.
• W2740806938 hasConcept C185592680 @default.
• W2740806938 hasConcept C2775838275 @default.
• W2740806938 hasConcept C2776151105 @default.
• W2740806938 hasConcept C2777302768 @default.
• W2740806938 hasConcept C2777352226 @default.
• W2740806938 hasConcept C2777810353 @default.
• W2740806938 hasConcept C2778004101 @default.
• W2740806938 hasConcept C2778760513 @default.
• W2740806938 hasConcept C2779054382 @default.
• W2740806938 hasConcept C2780829032 @default.
• W2740806938 hasConcept C55493867 @default.
• W2740806938 hasConcept C71924100 @default.
• W2740806938 hasConcept C98274493 @default.
• W2740806938 hasConceptScore W2740806938C126322002 @default.
• W2740806938 hasConceptScore W2740806938C134018914 @default.
• W2740806938 hasConceptScore W2740806938C185592680 @default.
• W2740806938 hasConceptScore W2740806938C2775838275 @default.
• W2740806938 hasConceptScore W2740806938C2776151105 @default.
• W2740806938 hasConceptScore W2740806938C2777302768 @default.
• W2740806938 hasConceptScore W2740806938C2777352226 @default.
• W2740806938 hasConceptScore W2740806938C2777810353 @default.
• W2740806938 hasConceptScore W2740806938C2778004101 @default.
• W2740806938 hasConceptScore W2740806938C2778760513 @default.
• W2740806938 hasConceptScore W2740806938C2779054382 @default.
• W2740806938 hasConceptScore W2740806938C2780829032 @default.
• W2740806938 hasConceptScore W2740806938C55493867 @default.
• W2740806938 hasConceptScore W2740806938C71924100 @default.
• W2740806938 hasConceptScore W2740806938C98274493 @default.
• W2740806938 hasLocation W27408069381 @default.
• W2740806938 hasOpenAccess W2740806938 @default.
• W2740806938 hasPrimaryLocation W27408069381 @default.
• W2740806938 hasRelatedWork W1698661136 @default.
• W2740806938 hasRelatedWork W1989194280 @default.
• W2740806938 hasRelatedWork W2005103041 @default.
• W2740806938 hasRelatedWork W2030465082 @default.
• W2740806938 hasRelatedWork W2186896172 @default.
• W2740806938 hasRelatedWork W2389280949 @default.
• W2740806938 hasRelatedWork W2392148861 @default.
• W2740806938 hasRelatedWork W2463248742 @default.
• W2740806938 hasRelatedWork W2792725032 @default.
• W2740806938 hasRelatedWork W2808768761 @default.
• W2740806938 hasRelatedWork W2969603814 @default.
• W2740806938 hasRelatedWork W2969719178 @default.
• W2740806938 hasRelatedWork W2986337089 @default.
• W2740806938 hasRelatedWork W3115636279 @default.

• next