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- W2740809741 abstract "Purpose of review The aim of this article is to examine significant advances in our understanding of the late respiratory effects of cancer treatment, including surgery, radiotherapy, chemotherapy, biological therapies and haematopoietic stem cell transplant, and to provide a framework for assessing such patients. Recent findings Oncology therapies have advanced considerably over recent years but pulmonary toxicity remains a concern. Advances have been made in our understanding of the risk factors, including genetic ones that lead to toxicity from radiotherapy and chemotherapy and risk stratification models are being developed to aid treatment planning. Targeted biological treatments are continuously being developed and consequently the Pneumotox database of pulmonary toxicity continues to be an essential resource. Early detection of bronchiolitis obliterans in haematopoietic stem cell transplant patients has been found to be critical, with some positive results from intervention trials. Summary Pulmonary toxicity is a common unwanted consequence of life enhancing or saving cancer treatments which remain difficult to treat. Developments in these fields are mainly in the areas of prevention, early detection and monitoring of unwanted side effects. We discuss some of these developments within this review." @default.
- W2740809741 created "2017-08-08" @default.
- W2740809741 creator A5081061312 @default.
- W2740809741 creator A5090709337 @default.
- W2740809741 date "2017-09-01" @default.
- W2740809741 modified "2023-10-16" @default.
- W2740809741 title "Late respiratory effects of cancer treatment" @default.
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- W2740809741 doi "https://doi.org/10.1097/spc.0000000000000286" @default.
- W2740809741 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28763349" @default.