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• W2740820430 abstract "Multidrug-resistant organisms are creating a challenge for physicians treating the critically ill. As new antibiotics lag behind the emergence of worsening resistance, intensivists in countries with high rates of extensively drug-resistant bacteria are turning to inhaled antibiotics as adjunctive therapy. These drugs can provide high concentrations of drug in the lung that could not be achieved with intravenous antibiotics without significant systemic toxicity. This article summarizes current evidence describing the use of inhaled antibiotics for the treatment of bacterial ventilator-associated pneumonia and ventilator-associated tracheobronchitis. Preliminary data suggest aerosolized antimicrobials may effectively treat resistant pathogens with high minimum inhibitory concentrations." @default.
• W2740820430 created "2017-08-08" @default.
• W2740820430 creator A5050953040 @default.
• W2740820430 date "2017-09-01" @default.
• W2740820430 modified "2023-09-25" @default.
• W2740820430 title "Inhaled Antibiotics for Ventilator-Associated Infections" @default.
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• W2740820430 doi "https://doi.org/10.1016/j.idc.2017.05.006" @default.
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