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• W2740883756 abstract "What is the prevalence and source of prospectively and retrospectively registered and unregistered trials in fertility treatments?Trial registration is low and does not appear to be changing over the 5 years studied.Trial registration is associated with lower risk of bias than in unregistered trials.The Cochrane Gynaecology and Fertility Group's specialised register was searched on 5 November 2015 for randomised controlled trials (RCTs) published from January 2010 to December 2014.Eligible trials included randomised women or men for fertility treatments, were published in full text, and written in English. Two reviewers independently assessed trial registration status for each trial, by searching the publication, trial registries, and by contacting the original authors.Of 693 eligible RCTS, only 44% were registered trials. Of 309 registered trials, 21.7% were prospectively registered, 15.8% were registered within 6 months of first patient enrolment and 62.5% were retrospectively registered trials. Prospective trial registration by country varied from 0% to 100%. The highest frequency of prospective trial registration amongst the top 10 publishing countries was 31% in the Netherlands.Only English language trials were included in this review.Prospective trial registration is still low. Journals, funders and ethics committees could have a greater role to increase trial registration.University of Auckland. No competing interests." @default.
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• W2740883756 date "2017-07-28" @default.
• W2740883756 modified "2023-09-26" @default.
• W2740883756 title "Clinical trial registration in fertility trials – a case for improvement?" @default.
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• W2740883756 doi "https://doi.org/10.1093/humrep/dex251" @default.
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