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- W2740982783 abstract "To the editor:Germ line–activating mutations of protein tyrosine phosphatase PTPN11 (Shp2), a positive regulator of the Ras signaling pathway,[1][1] account for more than 50% of patients with Noonan syndrome.[2][2] These patients have an increased risk of developing leukemias,[3][3] especially" @default.
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- W2740982783 date "2017-09-21" @default.
- W2740982783 modified "2023-10-16" @default.
- W2740982783 title "CCL3 is a key mediator for the leukemogenic effect of Ptpn11-activating mutations in the stem-cell microenvironment" @default.
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- W2740982783 doi "https://doi.org/10.1182/blood-2017-06-791103" @default.
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