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- W2740983983 abstract "Background: Pneumococcal pneumonia is still an important cause of mortality. The objective of this study was to compare frequency, clinical presen- tation, outcome and vaccination status of patients with pneumococcal community-acquired pneu- monia (CAP) to CAP due to other or no detected pathogen based on data of the German Network for community-acquired pneumonia (CAPNETZ). Methods: Demographic, clinical and diagnostic data were recorded using standardized web- based data acquisition. Standardized microbiolo- gical sampling and work-up were conducted in each patient. Results: 7400 patients with CAP from twelve clin- ical centers throughout Germany were included. In 2259 patients (32%) a pathogen was identified, Streptococcus pneumonia being the most frequent (n=676, 30% of all patients with identified patho- gens). Compared to those with non-pneumococ- cal pneumonia, patients with pneumococcal pneumonia were more frequently admitted to hospital (80% vs. 66%, p<0.001), had higher CURB score values on admission, had more fre- quently pleural effusion (19% vs. 14%, p=0.001) and needed more frequently oxygen insufflation (58% vs. 44%, p<0.001). There was no relevant difference in overall mortality. Conclusions: Pneumococcal pneumonia was asso- ciated with a more severe clinical course demand- ing more medical resources as compared to non- pneumococcal pneumonia. Zusammenfassung ! Hintergrund: Trotz Verfugbarkeit wirksamer Antibiotika ist die Pneumokokkenpneumonie weiterhin mit einer relevanten Mortalitat belas- tet. In der vorliegenden Arbeit wurden Haufig- keit, Symptomatik, Verlauf und Impfstatus von Patienten mit ambulant erworbener Pneumonie mit und ohne Nachweis von Pneumokokken ver-" @default.
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- W2740983983 date "2012-01-01" @default.
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- W2740983983 title "The Burden of Pneumococcal Pneumonia - Experience of the German Competence Network CAPNETZ Epidemiologie, Klinik und Verlauf der Pneumokokkenpneumonie - Daten aus CAPNETZ" @default.
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