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• W2741003062 abstract "<h3>Objective</h3> The evaluation of discomfort in paediatric research is scarcely evidence-based. In this study, we make a start in describing children9s self-reported discomfort during common medical research procedures and compare this with discomfort during dental check-ups which can be considered as a reference level of a ‘minimal discomfort’ medical procedure. We exploratory study whether there are associations between age, anxiety-proneness, gender, medical condition, previous experiences and discomfort. We also describe children9s suggestions for reducing discomfort. <h3>Design</h3> Cross-sectional descriptive study. <h3>Setting</h3> Paediatric research at three academic hospitals. <h3>Patients</h3> 357 children with and without illnesses (8–18 years, mean=10.6 years) were enrolled: 307 from paediatric research studies and 50 from dental care. <h3>Main outcome measures</h3> We measured various generic forms of discomfort (nervousness, annoyance, pain, fright, boredom, tiredness) due to six common research procedures: buccal swabs, MRI scans, pulmonary function tests, skin prick tests, ultrasound imaging and venepunctures. <h3>Results</h3> Most children reported limited discomfort during the research procedures (means: 1–2.6 on a scale from 1 to 5). Compared with dental check-ups, buccal swab tests, skin prick tests and ultrasound imaging were less discomforting, while MRI scans, venepunctures and pulmonary function tests caused a similar degree of discomfort. 60.3% of the children suggested providing distraction by showing movies to reduce discomfort. The exploratory analyses suggested a positive association between anxiety-proneness and discomfort. <h3>Conclusions</h3> The findings of this study support the acceptability of participation of children in the studied research procedures, which stimulates evidence-based research practice. Furthermore, the present study can be considered as a first step in providing benchmarks for discomfort of procedures in paediatric research." @default.
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• W2741003062 date "2017-07-01" @default.
• W2741003062 modified "2023-10-18" @default.
• W2741003062 title "The child's perspective on discomfort during medical research procedures: a descriptive study" @default.
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• W2741003062 doi "https://doi.org/10.1136/bmjopen-2017-016077" @default.
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