Matches in SemOpenAlex for { <https://semopenalex.org/work/W2741039898> ?p ?o ?g. }
- W2741039898 endingPage "10" @default.
- W2741039898 startingPage "1" @default.
- W2741039898 abstract "Neonatal lupus is a passively acquired autoimmune disease that occurs in offspring of mothers with anti-SSA/Ro and/or anti-SSB/ La antibodies. The primary clinical features are a photosensitive rash that is usually found on the scalp and periorbital areas, congenital heart block with or without cardiomyopathy, cytopenias, disseminated intravascular coagulation, and neonatal cholestasis with or without elevated transaminases. The diagnosis is usually made in utero by detection of a slow fetal heart rate and subsequent fetal echocardiographic confirmation of heart block and/or cardiomyopathy. Prenatal treatment with fluorinated glucocorticoids beginning as soon after detection has favourable outcome for mothers of fetuses with second degree heart block, is of no value for mothers of fetuses with third degree heart block, and controversial for mothers of fetuses with first degree heart block. Prenatal glucocorticoids can be used also in presence of cardiomyopathy associated with neonatal lupus. Hydroxychloroquine has been used in pregnant women who have anti-SSA/Ro antibodies and who have previously given birth to a child with cardiac manifestations. First and second degree block, detected in utero or at birth, can progress to complete heart block. Infants with complete heart block usually require a pacemaker with an excellent prognosis, although development of heart failure may occur." @default.
- W2741039898 created "2017-08-08" @default.
- W2741039898 creator A5000154265 @default.
- W2741039898 creator A5057237488 @default.
- W2741039898 creator A5079401191 @default.
- W2741039898 date "2014-10-20" @default.
- W2741039898 modified "2023-10-18" @default.
- W2741039898 title "Neonatal Lupus Erythematosus" @default.
- W2741039898 cites W105283528 @default.
- W2741039898 cites W1547382640 @default.
- W2741039898 cites W158358389 @default.
- W2741039898 cites W1606496874 @default.
- W2741039898 cites W187712674 @default.
- W2741039898 cites W1965275868 @default.
- W2741039898 cites W1967183300 @default.
- W2741039898 cites W1968628224 @default.
- W2741039898 cites W1970594753 @default.
- W2741039898 cites W1972368562 @default.
- W2741039898 cites W1973487882 @default.
- W2741039898 cites W1978023215 @default.
- W2741039898 cites W1982924404 @default.
- W2741039898 cites W1983137347 @default.
- W2741039898 cites W1987715953 @default.
- W2741039898 cites W1990143204 @default.
- W2741039898 cites W1995745997 @default.
- W2741039898 cites W1995950578 @default.
- W2741039898 cites W1996517245 @default.
- W2741039898 cites W1997131650 @default.
- W2741039898 cites W2001836991 @default.
- W2741039898 cites W2003006953 @default.
- W2741039898 cites W2004064425 @default.
- W2741039898 cites W2005105087 @default.
- W2741039898 cites W2006681681 @default.
- W2741039898 cites W2007176585 @default.
- W2741039898 cites W2008897872 @default.
- W2741039898 cites W2014024398 @default.
- W2741039898 cites W2018760560 @default.
- W2741039898 cites W2023909701 @default.
- W2741039898 cites W2026752890 @default.
- W2741039898 cites W2029539614 @default.
- W2741039898 cites W2032009846 @default.
- W2741039898 cites W2034101628 @default.
- W2741039898 cites W2034440477 @default.
- W2741039898 cites W2037433854 @default.
- W2741039898 cites W2037673274 @default.
- W2741039898 cites W2037952732 @default.
- W2741039898 cites W2039052107 @default.
- W2741039898 cites W2040134794 @default.
- W2741039898 cites W2040657208 @default.
- W2741039898 cites W2040866409 @default.
- W2741039898 cites W2041510163 @default.
- W2741039898 cites W2042025295 @default.
- W2741039898 cites W2044438526 @default.
- W2741039898 cites W2046023606 @default.
- W2741039898 cites W2047448176 @default.
- W2741039898 cites W2048196739 @default.
- W2741039898 cites W2049795239 @default.
- W2741039898 cites W2050059762 @default.
- W2741039898 cites W2050881712 @default.
- W2741039898 cites W2054495051 @default.
- W2741039898 cites W2054992677 @default.
- W2741039898 cites W2062920936 @default.
- W2741039898 cites W2062944200 @default.
- W2741039898 cites W2069255656 @default.
- W2741039898 cites W2069336652 @default.
- W2741039898 cites W2069727915 @default.
- W2741039898 cites W2070185031 @default.
- W2741039898 cites W2073483582 @default.
- W2741039898 cites W2074960079 @default.
- W2741039898 cites W2077442450 @default.
- W2741039898 cites W2078383879 @default.
- W2741039898 cites W2078907753 @default.
- W2741039898 cites W2079925961 @default.
- W2741039898 cites W2080285185 @default.
- W2741039898 cites W2080444921 @default.
- W2741039898 cites W2085001130 @default.
- W2741039898 cites W2090302159 @default.
- W2741039898 cites W2093686935 @default.
- W2741039898 cites W2094612275 @default.
- W2741039898 cites W2096935199 @default.
- W2741039898 cites W2097558397 @default.
- W2741039898 cites W2097847031 @default.
- W2741039898 cites W2098400732 @default.
- W2741039898 cites W2105436590 @default.
- W2741039898 cites W2112321962 @default.
- W2741039898 cites W2112559914 @default.
- W2741039898 cites W2115561370 @default.
- W2741039898 cites W2123799682 @default.
- W2741039898 cites W2125111321 @default.
- W2741039898 cites W2128083871 @default.
- W2741039898 cites W2132713366 @default.
- W2741039898 cites W2135804917 @default.
- W2741039898 cites W2138176993 @default.
- W2741039898 cites W2143834163 @default.
- W2741039898 cites W2145904199 @default.
- W2741039898 cites W2148402927 @default.
- W2741039898 cites W2150840069 @default.
- W2741039898 cites W2154635550 @default.