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- W2741080858 abstract "Summary Objectives: A systemic vascular effect of beta2-adrenergic agonist salbutamol is partially mediated through the L-arginine‐NO pathway. Therefore, the attenuation of photoplethysmographic digital volume pulse parameters under salbutamol inhalation could be used for the evaluation of endothelial function. The aim of the study was to estimate the vascular response to salbutamol in patients with arterial hypertension (AH) and coronary heart disease (CHD). Design and Methods: Totally 71 subjects were studied: 30 patients with AH, 26 patients with CHD and 15 healthy controls (C). All the subjects underwent the detailed clinical assessment and photoplethysmographic evaluation of the pulse wave response to 400 µg salbutamol inhalation. A portable photoplethysmograph Micro Medical MP2000 (Gillingham, Kent, United Kingdom) was used for digital volume pulse analysis. The assessment was performed according to the modified protocol of Chowienczyk et al. Results: Characteristic change in the pulse wave curve after salbutamol inhalation was observed in the controls: a decrease in the height of the inflection point (IP) (∆IP 18.24 ± 16.42, p 0.05). Conclusion: Our findings suggest that impaired vasomotor endothelial function could be responsible for a blunted response of the pulse wave parameters to salbutamol in hypertensive and coronary patients. Seminars in Cardiology 2004; 10(2): 83–90" @default.
- W2741080858 created "2017-08-08" @default.
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- W2741080858 date "2004-01-01" @default.
- W2741080858 modified "2023-09-23" @default.
- W2741080858 title "Photoplethysmographic assessment of the pulse wave: a blunted response to salbutamol in arterial hypertension and coronary artery disease" @default.
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