Matches in SemOpenAlex for { <https://semopenalex.org/work/W2741191074> ?p ?o ?g. }
- W2741191074 endingPage "61" @default.
- W2741191074 startingPage "51" @default.
- W2741191074 abstract "The study demonstrates the effects of chronic sub-lethal exposure of sodium fluoride (NaF) on reproductive structure and function of female Drosophila melanogaster. As a part of treatment, flies were maintained in food supplemented with sub-lethal concentrations of NaF (10–100 μg/mL). Fecundity, ovarian morphology, presence and profusion of viable cells from ovary and fat body were taken into consideration for evaluating changes in reproductive homeostasis. Wing length (a factor demonstrating body size and reproductive fitness) was also monitored after NaF exposure. Significant reduction in fecundity, alteration in ovarian morphology along with an increase in apoptosis was observed in treated females. Simultaneous decline in viable cell number and larval weight validates the result of MTT assay. Furthermore, altered ovarian Glucose-6-phosphate dehydrogenase and catalase activities together with increased rate of lipid peroxidation after 20 and 40 μg/mL NaF exposure confirmed the changes in reproduction related metabolism. Enhanced lipid peroxidation known for ROS generation might have induced genotoxicity which is confirmed through Comet assay. The enzyme activities were not dose dependent, rather manifested a bimodal response, which suggests a well-knit interaction among the players inducing stress and the ones that help establish physiological homeostasis." @default.
- W2741191074 created "2017-08-08" @default.
- W2741191074 creator A5008689778 @default.
- W2741191074 creator A5023235240 @default.
- W2741191074 creator A5033030403 @default.
- W2741191074 creator A5041174301 @default.
- W2741191074 date "2017-11-01" @default.
- W2741191074 modified "2023-09-25" @default.
- W2741191074 title "Sodium fluoride adversely affects ovarian development and reproduction in Drosophila melanogaster" @default.
- W2741191074 cites W1601791950 @default.
- W2741191074 cites W1775749144 @default.
- W2741191074 cites W1970159856 @default.
- W2741191074 cites W1971159072 @default.
- W2741191074 cites W1973393334 @default.
- W2741191074 cites W1974054643 @default.
- W2741191074 cites W1978574727 @default.
- W2741191074 cites W1983310681 @default.
- W2741191074 cites W1983862855 @default.
- W2741191074 cites W1986033100 @default.
- W2741191074 cites W1989357597 @default.
- W2741191074 cites W1992947736 @default.
- W2741191074 cites W1997572376 @default.
- W2741191074 cites W2003544119 @default.
- W2741191074 cites W2006849426 @default.
- W2741191074 cites W2009202775 @default.
- W2741191074 cites W2010028138 @default.
- W2741191074 cites W2014997440 @default.
- W2741191074 cites W2022037408 @default.
- W2741191074 cites W2026669179 @default.
- W2741191074 cites W2042270904 @default.
- W2741191074 cites W2045158080 @default.
- W2741191074 cites W2054958213 @default.
- W2741191074 cites W2058341483 @default.
- W2741191074 cites W2066357993 @default.
- W2741191074 cites W2066688287 @default.
- W2741191074 cites W2078388509 @default.
- W2741191074 cites W2085389891 @default.
- W2741191074 cites W2087904755 @default.
- W2741191074 cites W2089950231 @default.
- W2741191074 cites W2095296974 @default.
- W2741191074 cites W2096795975 @default.
- W2741191074 cites W2099887769 @default.
- W2741191074 cites W2100979447 @default.
- W2741191074 cites W2104073781 @default.
- W2741191074 cites W2114570645 @default.
- W2741191074 cites W2116015578 @default.
- W2741191074 cites W2121429522 @default.
- W2741191074 cites W2121789967 @default.
- W2741191074 cites W2122842079 @default.
- W2741191074 cites W2123974476 @default.
- W2741191074 cites W2125955205 @default.
- W2741191074 cites W2318893785 @default.
- W2741191074 cites W2415639538 @default.
- W2741191074 cites W2527117509 @default.
- W2741191074 cites W307698176 @default.
- W2741191074 doi "https://doi.org/10.1016/j.chemosphere.2017.07.123" @default.
- W2741191074 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28763637" @default.
- W2741191074 hasPublicationYear "2017" @default.
- W2741191074 type Work @default.
- W2741191074 sameAs 2741191074 @default.
- W2741191074 citedByCount "26" @default.
- W2741191074 countsByYear W27411910742018 @default.
- W2741191074 countsByYear W27411910742019 @default.
- W2741191074 countsByYear W27411910742020 @default.
- W2741191074 countsByYear W27411910742021 @default.
- W2741191074 countsByYear W27411910742022 @default.
- W2741191074 countsByYear W27411910742023 @default.
- W2741191074 crossrefType "journal-article" @default.
- W2741191074 hasAuthorship W2741191074A5008689778 @default.
- W2741191074 hasAuthorship W2741191074A5023235240 @default.
- W2741191074 hasAuthorship W2741191074A5033030403 @default.
- W2741191074 hasAuthorship W2741191074A5041174301 @default.
- W2741191074 hasConcept C104317684 @default.
- W2741191074 hasConcept C126322002 @default.
- W2741191074 hasConcept C134018914 @default.
- W2741191074 hasConcept C143425029 @default.
- W2741191074 hasConcept C16685009 @default.
- W2741191074 hasConcept C179104552 @default.
- W2741191074 hasConcept C185592680 @default.
- W2741191074 hasConcept C2776151105 @default.
- W2741191074 hasConcept C2778324911 @default.
- W2741191074 hasConcept C2778959862 @default.
- W2741191074 hasConcept C2778979269 @default.
- W2741191074 hasConcept C2779234887 @default.
- W2741191074 hasConcept C2780104201 @default.
- W2741191074 hasConcept C2780358455 @default.
- W2741191074 hasConcept C2780828025 @default.
- W2741191074 hasConcept C2780829032 @default.
- W2741191074 hasConcept C2908647359 @default.
- W2741191074 hasConcept C29730261 @default.
- W2741191074 hasConcept C33070731 @default.
- W2741191074 hasConcept C54355233 @default.
- W2741191074 hasConcept C552990157 @default.
- W2741191074 hasConcept C55493867 @default.
- W2741191074 hasConcept C59659247 @default.
- W2741191074 hasConcept C63645605 @default.
- W2741191074 hasConcept C67283656 @default.
- W2741191074 hasConcept C71924100 @default.