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- W2741388206 abstract "Congenital Cytomegalovirus (CMV) infection occurs in 0.6-0.7% of newborns and represents the most frequent infectious cause of congenital neurologic handicap. Vertical transmission occurs in approximately 30% of cases, but the fetus isn’t always affected. Symptomatic newborns present a higher risk for severe neurological sequelae. CMV screening should be reserved for suspected primary infection during pregnancy or for pregnant women considered at risk, so the indications are very wide. Serum IgG and IgM detection and IgG avidity seem to be the most reliable tests to identify a primary infection, although their interpretation in clinical context may be difficult. In the absence of confirmed fetal infection with structural fetal anomalies identified, pregnancy termination should be discouraged. Fetal outcome is mainly correlated with the cerebral involvement. Despite promising results regarding medical treatment with antivirals and hyperimmune globulin (HIG), results must be carefully interpreted." @default.
- W2741388206 created "2017-08-08" @default.
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- W2741388206 date "2017-06-16" @default.
- W2741388206 modified "2023-10-18" @default.
- W2741388206 title "Infecţia cu citomegalovirus în sarcină - 10 întrebări, 10 răspunsuri" @default.
- W2741388206 hasPublicationYear "2017" @default.
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