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- W2741938629 abstract "+OBJECTIVE: To compare the frequency of brain tumor signs and symptoms in children with and without brain tumors. METHODS: This was a UK population-based retrospective analysis of primary care records. Participants were 195 children (1–14 years) newly diagnosed with brain tumors and 285 controls matched by age, gender, and region. Comparisons included total number of prediagnosis consultations, number with 1 symptom suggestive of a brain tumor, total number of symptoms, number of different symptoms, and number of visits with specific combinations of symptoms. RESULTS: On average, cases consulted more often than controls between birth and diagnosis/pseudodiagnosis with brain tumor signs and symptoms. Their consultation rate with 1 suggestive symptom escalated in the 2 years before diagnosis. Symptom prevalence was higher among cases than controls, a relative difference of 3.29 times as many consultations with 1 suggestive symptom (95% confidence interval [CI]: 2.82–3.83) and 7.01 as many with more than 1 (95% CI: 5.38 –9.13). In each 6-month period in the 4 years before diagnosis, cases had at least twice as many consultations with 1 suggestive symptom (20.81 times as many in the 6 months before diagnosis [95% CI: 14.29 –30.30]) and 2–3 times more records of suggestive symptoms (28.35 times more in the 6 months before diagnosis [95% CI: 19.05– 42.19]). Symptoms rarely or not observed among control children included head tilt, odd head movements, odd posture, back or neck stiffness, and unsteadiness without obvious cause." @default.
- W2741938629 created "2017-08-08" @default.
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- W2741938629 date "2017-01-01" @default.
- W2741938629 modified "2023-09-24" @default.
- W2741938629 title "Brain Tumor Signs and Symptoms: Analysis of Primary Health Care Records From the UKCCS WHAT'S KNOWN ON THIS SUBJECT: Good information on" @default.
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