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• W2742133635 abstract "Toll-like receptors (TLRs) play a central role in innate immunity as pathogen sensors. During the last decade, structural analyses of TLRs have revealed the mechanisms of ligand recognition and signal transduction. Each TLR recognizes its cognate ligand in a different manner, whereas signal transduction is achieved by a common mechanism. In this review, the mechanisms of ligand recognition and signal transduction by TLRs are summarized based on recent structural information." @default.
• W2742133635 created "2017-08-08" @default.
• W2742133635 creator A5056464997 @default.
• W2742133635 date "2017-01-01" @default.
• W2742133635 modified "2023-10-16" @default.
• W2742133635 title "Conservation and Divergence of Ligand Recognition and Signal Transduction Mechanisms in Toll-Like Receptors" @default.
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• W2742133635 doi "https://doi.org/10.1248/cpb.c17-00323" @default.
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