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- W2742430378 abstract "Abstract Recently alignment-free sequence comparison methods based on promoter-frequency distance measures have gained popularity. This paper reports on the implementation and validation of several alignment-free sequence analysis methods for representing and quantifying between-sequence distances and sequence variability. The msktuple library includes the following sequence comparison techniques: locational k-tuple, naive k-tuple, CV-Tree, and their ensemble variants. These metrics are used to determine the dissimilarity between sequences using k-letter words. In support of open-science , we provide open-source software, R-scripts, and protocols implementing the new techniques. These tools will support collaboration, enable independent validation, promote result reproducibility and enable tool interoperability." @default.
- W2742430378 created "2017-08-17" @default.
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- W2742430378 date "2017-09-01" @default.
- W2742430378 modified "2023-09-26" @default.
- W2742430378 title "msktuple: An integrated R library for alignment-free multiple sequence k-tuple analysis" @default.
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- W2742430378 doi "https://doi.org/10.1016/j.chemolab.2017.07.012" @default.
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