FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2742495787> ?p ?o ?g. }

• W2742495787 endingPage "5003" @default.
• W2742495787 startingPage "4995" @default.
• W2742495787 abstract "Distortion of DNA can inhibit transcription and replication, resulting in cell death. The nucleotide excision repair (NER) pathway recognizes and repairs DNA adducts. Excision repair cross-complementation group 1 (ERCC1) is a nuclease that serves a vital role in the NER pathway. Few studies have investigated ERCC1 expression in breast cancer. The aim of the present study was to analyze the association between clinicopathological features and ERCC1 expression in breast cancer. ERCC1 expression was studied in 224 invasive ductal carcinomas by immunohistochemical staining. ERCC1 expression was analyzed as an immunoreactive score, and classified into low and high expression groups. The association between immunohistochemical parameters and clinicopathological features was evaluated. High expression of ERCC1 was observed in 33 cases (14.7%) and was statistically associated with lower T stage (P=0.005), lower tumor size (P=0.001), no lymph node metastasis (P=0.044) and no lymphovascular invasion (LVI; P=0.004). Additionally, high ERCC1 expression was associated with a positive estrogen receptor (ER) (P=0.006) and progesterone receptor (PR) (P=0.001) expression status. Non-triple-negative breast carcinoma occurred more frequently in the high expression group (97%) than the low expression group; however, the difference was not statistically significant (P=0.056). Overall and disease-free survival were also not significantly different between the two groups (P=0.989 and P=0.215, respectively). In conclusion, high ERCC1 expression is statistically associated with lower T stage, smaller tumor size, no lymph node metastasis, no LVI, and positive ER and PR expression. This suggests that ERCC1 is associated with favorable prognostic parameters in breast cancer." @default.
• W2742495787 created "2017-08-17" @default.
• W2742495787 creator A5024409808 @default.
• W2742495787 creator A5041099873 @default.
• W2742495787 creator A5046537693 @default.
• W2742495787 creator A5053370463 @default.
• W2742495787 creator A5059760054 @default.
• W2742495787 creator A5082344550 @default.
• W2742495787 date "2017-08-09" @default.
• W2742495787 modified "2023-09-30" @default.
• W2742495787 title "High excision repair cross-complementation group 1 expression is associated with favorable prognostic factors in breast cancer" @default.
• W2742495787 cites W1829077072 @default.
• W2742495787 cites W1946519357 @default.
• W2742495787 cites W1963517973 @default.
• W2742495787 cites W1967186439 @default.
• W2742495787 cites W1986383075 @default.
• W2742495787 cites W1998646002 @default.
• W2742495787 cites W2044702943 @default.
• W2742495787 cites W2048939997 @default.
• W2742495787 cites W2062444881 @default.
• W2742495787 cites W2073941859 @default.
• W2742495787 cites W2084415574 @default.
• W2742495787 cites W2087239876 @default.
• W2742495787 cites W2093736774 @default.
• W2742495787 cites W2097255042 @default.
• W2742495787 cites W2101979288 @default.
• W2742495787 cites W2103249524 @default.
• W2742495787 cites W2108957985 @default.
• W2742495787 cites W2112974030 @default.
• W2742495787 cites W2115847479 @default.
• W2742495787 cites W2125094267 @default.
• W2742495787 cites W2130177169 @default.
• W2742495787 cites W2157963272 @default.
• W2742495787 cites W2163885210 @default.
• W2742495787 cites W2170529005 @default.
• W2742495787 cites W2170961135 @default.
• W2742495787 cites W2259802687 @default.
• W2742495787 cites W2340386540 @default.
• W2742495787 cites W2342433221 @default.
• W2742495787 cites W2348321689 @default.
• W2742495787 cites W1554814573 @default.
• W2742495787 doi "https://doi.org/10.3892/ol.2017.6737" @default.
• W2742495787 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5594248" @default.
• W2742495787 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28943968" @default.
• W2742495787 hasPublicationYear "2017" @default.
• W2742495787 type Work @default.
• W2742495787 sameAs 2742495787 @default.
• W2742495787 citedByCount "5" @default.
• W2742495787 countsByYear W27424957872018 @default.
• W2742495787 countsByYear W27424957872019 @default.
• W2742495787 countsByYear W27424957872021 @default.
• W2742495787 crossrefType "journal-article" @default.
• W2742495787 hasAuthorship W2742495787A5024409808 @default.
• W2742495787 hasAuthorship W2742495787A5041099873 @default.
• W2742495787 hasAuthorship W2742495787A5046537693 @default.
• W2742495787 hasAuthorship W2742495787A5053370463 @default.
• W2742495787 hasAuthorship W2742495787A5059760054 @default.
• W2742495787 hasAuthorship W2742495787A5082344550 @default.
• W2742495787 hasBestOaLocation W27424957871 @default.
• W2742495787 hasConcept C104317684 @default.
• W2742495787 hasConcept C104451858 @default.
• W2742495787 hasConcept C121608353 @default.
• W2742495787 hasConcept C126322002 @default.
• W2742495787 hasConcept C134935766 @default.
• W2742495787 hasConcept C142724271 @default.
• W2742495787 hasConcept C143998085 @default.
• W2742495787 hasConcept C204232928 @default.
• W2742495787 hasConcept C2778740770 @default.
• W2742495787 hasConcept C2779013556 @default.
• W2742495787 hasConcept C2779309665 @default.
• W2742495787 hasConcept C502942594 @default.
• W2742495787 hasConcept C530470458 @default.
• W2742495787 hasConcept C55493867 @default.
• W2742495787 hasConcept C71924100 @default.
• W2742495787 hasConcept C86803240 @default.
• W2742495787 hasConceptScore W2742495787C104317684 @default.
• W2742495787 hasConceptScore W2742495787C104451858 @default.
• W2742495787 hasConceptScore W2742495787C121608353 @default.
• W2742495787 hasConceptScore W2742495787C126322002 @default.
• W2742495787 hasConceptScore W2742495787C134935766 @default.
• W2742495787 hasConceptScore W2742495787C142724271 @default.
• W2742495787 hasConceptScore W2742495787C143998085 @default.
• W2742495787 hasConceptScore W2742495787C204232928 @default.
• W2742495787 hasConceptScore W2742495787C2778740770 @default.
• W2742495787 hasConceptScore W2742495787C2779013556 @default.
• W2742495787 hasConceptScore W2742495787C2779309665 @default.
• W2742495787 hasConceptScore W2742495787C502942594 @default.
• W2742495787 hasConceptScore W2742495787C530470458 @default.
• W2742495787 hasConceptScore W2742495787C55493867 @default.
• W2742495787 hasConceptScore W2742495787C71924100 @default.
• W2742495787 hasConceptScore W2742495787C86803240 @default.
• W2742495787 hasIssue "4" @default.
• W2742495787 hasLocation W27424957871 @default.
• W2742495787 hasLocation W27424957872 @default.
• W2742495787 hasLocation W27424957873 @default.
• W2742495787 hasLocation W27424957874 @default.
• W2742495787 hasOpenAccess W2742495787 @default.
• W2742495787 hasPrimaryLocation W27424957871 @default.

• next