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• W2742539834 startingPage "9682" @default.
• W2742539834 abstract "A straightforward method for the synthesis of functionalized imidazo[2,1-b]thiazoles starting from benzaldehydes, 2-aminothiazoles, and alkynes under copper(I,II) catalysis was developed. The protocol allows the construction of a variety of aryl-substituted imidazo[2,1-b]benzothiazoles, -[2,1-b]thiazoles, and -[2,1-b][1,3,4]thiadiazoles. The reactions were easy to perform affording most of the desired products in 33-93% yields. The intensification of the process in a continuous-flow reactor increases the products' yields up to quantitative." @default.
• W2742539834 created "2017-08-17" @default.
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• W2742539834 date "2017-08-25" @default.
• W2742539834 modified "2023-10-16" @default.
• W2742539834 title "Synthesis of Imidazo[2,1-<i>b</i>]thiazoles via Copper-Catalyzed A³-Coupling in Batch and Continuous Flow" @default.
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• W2742539834 doi "https://doi.org/10.1021/acs.joc.7b01762" @default.
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