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- W2742605565 abstract "Publisher Summary This chapter discusses the evolutionary aspects of neuropeptides. The chapter discusses the rapid increase of the knowledge of the distribution, diversity, molecular structure, gene coding, and functions of neuropeptides in mammals. Peptide-producing neurones have been identified in representatives of all animal phyla, with the exception of the sponges. Application of antisera to numerous biologically active vertebrate peptides resulted in the identification of a great diversity of peptidergic neurones in invertebrates. The chapter focuses on the neuropeptides of molluscs. Many gastro-entero-pancreatic neurohormonal peptides have a long phylogenetic history. Peptides similar to, or identical with cholecystokinin, substance P, neurotensin and bombesin are found in the primitive nervous systems of coelenterates. The selection pressure on functionally important peptides results in conservation of the molecular structure of these peptides, whereas non-functional peptides escape from this selection. The organization of the multifunctional precursors of the egg-laying systems of snails allows speculating about their evolutionary origin." @default.
- W2742605565 created "2017-08-17" @default.
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- W2742605565 date "1987-01-01" @default.
- W2742605565 modified "2023-09-26" @default.
- W2742605565 title "Chapter 4 Evolutionary aspects of neuropeptides" @default.
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- W2742605565 doi "https://doi.org/10.1016/s0079-6123(08)60194-6" @default.
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