FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2742932112> ?p ?o ?g. }

• W2742932112 endingPage "3147" @default.
• W2742932112 startingPage "3136" @default.
• W2742932112 abstract "Bacterial infection of implanted biomaterials is a serious problem that increases health care costs and negatively affects a considerable fraction of orthopedic procedures. In this field, magnesium oxide nanoparticles (MgO NPs) have emerged as a promising material to combat bacterial infection while maintaining or improving bone cell functions. Here, MgO NPs were electrophoretically deposited onto poly-L-lactic acid (PLLA) sheets to achieve a coating of highly exposed MgO NPs that directly influenced cell-substrate interactions at short time scales. Samples were characterized for their surface chemistry, crystal structure, roughness, wettability, degradation characteristics, and their ability to support the growth of human fibroblasts and osteoblasts, as well as their resistance to colonization by Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa. In general, increasing the applied voltage during deposition increased the surface coverage of the coating and significantly decreased the colonization of all three bacterial strains (up to a 90% reduction). Furthermore, S. aureus cells that did attach onto substrates prepared at high voltages exhibited trademark signs of membrane damage and cell death. Importantly, MTS cell viability assays indicated that osteoblast adhesion increased with increasing deposition voltage, while fibroblast adhesion exhibited the opposite trend. Thus, although requiring more studies, this research provides the first evidence that MgO NP coatings prepared at relatively high voltages (120-150 V) may have the ability to resist bacterial colonization, promote bone cell attachment, and curb fibrous capsule formation. Therefore, it is recommended that this technology be further investigated and developed for numerous orthopedic applications. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 3136-3147, 2017." @default.
• W2742932112 created "2017-08-17" @default.
• W2742932112 creator A5014605237 @default.
• W2742932112 creator A5076201188 @default.
• W2742932112 creator A5085336186 @default.
• W2742932112 date "2017-08-24" @default.
• W2742932112 modified "2023-10-09" @default.
• W2742932112 title "Electrophoretic deposition of MgO nanoparticles imparts antibacterial properties to poly‐L‐lactic acid for orthopedic applications" @default.
• W2742932112 cites W1600090814 @default.
• W2742932112 cites W1976697629 @default.
• W2742932112 cites W1977531147 @default.
• W2742932112 cites W1983040770 @default.
• W2742932112 cites W1998169669 @default.
• W2742932112 cites W2005108684 @default.
• W2742932112 cites W2014932842 @default.
• W2742932112 cites W2017853377 @default.
• W2742932112 cites W2019150383 @default.
• W2742932112 cites W2028057171 @default.
• W2742932112 cites W2031637644 @default.
• W2742932112 cites W2042094339 @default.
• W2742932112 cites W2044575726 @default.
• W2742932112 cites W2054207534 @default.
• W2742932112 cites W2055630021 @default.
• W2742932112 cites W2074584584 @default.
• W2742932112 cites W2075945587 @default.
• W2742932112 cites W2078798878 @default.
• W2742932112 cites W2092127745 @default.
• W2742932112 cites W2094012282 @default.
• W2742932112 cites W2095024187 @default.
• W2742932112 cites W2106060595 @default.
• W2742932112 cites W2108851629 @default.
• W2742932112 cites W2139023389 @default.
• W2742932112 cites W2147909568 @default.
• W2742932112 cites W2181625897 @default.
• W2742932112 cites W4234629156 @default.
• W2742932112 doi "https://doi.org/10.1002/jbm.a.36174" @default.
• W2742932112 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28782240" @default.
• W2742932112 hasPublicationYear "2017" @default.
• W2742932112 type Work @default.
• W2742932112 sameAs 2742932112 @default.
• W2742932112 citedByCount "20" @default.
• W2742932112 countsByYear W27429321122018 @default.
• W2742932112 countsByYear W27429321122019 @default.
• W2742932112 countsByYear W27429321122020 @default.
• W2742932112 countsByYear W27429321122021 @default.
• W2742932112 countsByYear W27429321122022 @default.
• W2742932112 crossrefType "journal-article" @default.
• W2742932112 hasAuthorship W2742932112A5014605237 @default.
• W2742932112 hasAuthorship W2742932112A5076201188 @default.
• W2742932112 hasAuthorship W2742932112A5085336186 @default.
• W2742932112 hasConcept C12554922 @default.
• W2742932112 hasConcept C127413603 @default.
• W2742932112 hasConcept C134514944 @default.
• W2742932112 hasConcept C1491633281 @default.
• W2742932112 hasConcept C155672457 @default.
• W2742932112 hasConcept C159985019 @default.
• W2742932112 hasConcept C171250308 @default.
• W2742932112 hasConcept C185592680 @default.
• W2742932112 hasConcept C192562407 @default.
• W2742932112 hasConcept C2775891822 @default.
• W2742932112 hasConcept C2777949923 @default.
• W2742932112 hasConcept C2779489039 @default.
• W2742932112 hasConcept C2781448156 @default.
• W2742932112 hasConcept C42360764 @default.
• W2742932112 hasConcept C523546767 @default.
• W2742932112 hasConcept C53227056 @default.
• W2742932112 hasConcept C54355233 @default.
• W2742932112 hasConcept C55493867 @default.
• W2742932112 hasConcept C84416704 @default.
• W2742932112 hasConcept C85789140 @default.
• W2742932112 hasConcept C86803240 @default.
• W2742932112 hasConcept C89423630 @default.
• W2742932112 hasConceptScore W2742932112C12554922 @default.
• W2742932112 hasConceptScore W2742932112C127413603 @default.
• W2742932112 hasConceptScore W2742932112C134514944 @default.
• W2742932112 hasConceptScore W2742932112C1491633281 @default.
• W2742932112 hasConceptScore W2742932112C155672457 @default.
• W2742932112 hasConceptScore W2742932112C159985019 @default.
• W2742932112 hasConceptScore W2742932112C171250308 @default.
• W2742932112 hasConceptScore W2742932112C185592680 @default.
• W2742932112 hasConceptScore W2742932112C192562407 @default.
• W2742932112 hasConceptScore W2742932112C2775891822 @default.
• W2742932112 hasConceptScore W2742932112C2777949923 @default.
• W2742932112 hasConceptScore W2742932112C2779489039 @default.
• W2742932112 hasConceptScore W2742932112C2781448156 @default.
• W2742932112 hasConceptScore W2742932112C42360764 @default.
• W2742932112 hasConceptScore W2742932112C523546767 @default.
• W2742932112 hasConceptScore W2742932112C53227056 @default.
• W2742932112 hasConceptScore W2742932112C54355233 @default.
• W2742932112 hasConceptScore W2742932112C55493867 @default.
• W2742932112 hasConceptScore W2742932112C84416704 @default.
• W2742932112 hasConceptScore W2742932112C85789140 @default.
• W2742932112 hasConceptScore W2742932112C86803240 @default.
• W2742932112 hasConceptScore W2742932112C89423630 @default.
• W2742932112 hasFunder F4320306076 @default.
• W2742932112 hasIssue "11" @default.
• W2742932112 hasLocation W27429321121 @default.
• W2742932112 hasLocation W27429321122 @default.

• next