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- W2743003440 abstract "Aim: Proprotein convertase subtilisin/kexin 9 (PCSK9), a protein regulating the number of cell-surface low-density lipoprotein (LDL) receptors (LDL-R), circulates partially associated to LDL, high-density lipoproteins (HDL) and lipoprotein (a). How this interaction alters PCSK9 plasma levels is still unclear. In the present study, we investigated whether a condition of familial hypoalphalipoproteinemia (FHA), due to genetic mutations in LCAT, ABCA1 or APOAI genes, could alter PCSK9 levels and distribution among different lipoproteins." @default.
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- W2743003440 date "2017-08-01" @default.
- W2743003440 modified "2023-10-03" @default.
- W2743003440 title "Plasma PCSK9 levels and lipoprotein distribution are preserved in patients with severe hypoalphalipoproteinemia" @default.
- W2743003440 doi "https://doi.org/10.1016/j.atherosclerosis.2017.06.295" @default.
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