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- W2743016098 abstract "Background: While outcomes of patients with amyloid cardiomyopathy (ACM) undergoing heart transplantation have been studied, there is scant data on the wait-list mortality of these patients. We sought to investigate whether patients with amyloid cardiomyopathy had higher wait-list mortality compared to those with other types of cardiomyopathies. Methods: We queried the United Network for Organ Sharing (UNOS) registry for all patients (age ≥ 18 years) listed for heart transplantation between 2008 and 2015. We compared patients with ACM to those with dilated cardiomyopathy (DCM) or idiopathic restrictive cardiomyopathy (RCM) for waitlist mortality (WLM) and wait-list mortality or delisting for deterioration (WLMD). Results: We identified 306 patients with ACM, 183 with RCM and 8416 with DCM. Patients with ACM were older (ACM 61 vs RCM 49 vs DCM 51 years, P < .001), were more likely to be male (82% vs 60% vs 73%, P < .001), but less likely to be listed as status 1A (16% vs 18% vs 23%, P < .001). Compared with DCM, patients with ACM had increased WLM (adjusted HR 2.71 [1.94–3.78], P < .001, Fig. 1) and WLMD (adjusted HR 2.57 [2.02–3.27], P < .001). There was no difference between ACM and RCM in WLM (P = .14) or WLMD (P = .52). Conclusion: Patients with amyloid cardiomyopathy are listed with lower acuity, and have higher waitlist mortality compared with dilated cardiomyopathies. These findings should be considered for listing priority and organ allocation in AC." @default.
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- W2743016098 date "2017-08-01" @default.
- W2743016098 modified "2023-10-16" @default.
- W2743016098 title "Amyloid Cardiomyopathy and Waitlist Mortality in the United States: Implications for Organ Allocation" @default.
- W2743016098 doi "https://doi.org/10.1016/j.cardfail.2017.07.368" @default.
- W2743016098 hasPublicationYear "2017" @default.
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