FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2743111064> ?p ?o ?g. }

• W2743111064 endingPage "9573" @default.
• W2743111064 startingPage "9567" @default.
• W2743111064 abstract "Biothiols, including cysteine (Cys), homocysteine (Hcy), and glutathione (GSH), play a crucial role in many physiological processes. Cys production and metabolism is closely connected with Hcy and GSH; meanwhile, the dynamic antioxidant defenses network by Cys is independent of the GSH system, and Cys can serve as a more effective biomarker of oxidative stress. Hence, it is significant and urgent to develop an efficient method for specific detection of Cys over other biothiols (Hcy/GSH). However, most of the present Cys-specific fluorescent probes distinguished Cys from Hcy through response time, which would suffer from an unavoidable interference from Hcy in long-time detection. In this work, in order to improve the selectivity, we employed an improved aromatic substitution-rearrangement strategy to develop a ratiometric Cys-specific fluorescent probe (Cou-SBD-Cl) based on a new fluorescence resonance energy transfer (FRET) coumarin-sulfonyl benzoxadiazole (Cou-SBD) platform for discrimination of Hcy and GSH. Response of Cou-SBD-Cl to Cys would switch FRET on and generate a new yellow fluorescence emission with a 56.1-fold enhancement of ratio signal and a 99 nm emission shift. The desirable dual-color ratiometric imaging was achieved in living cells and normal zebrafish. In addition, probe Cou-SBD-Cl was also applied to real-time monitor Cys fluctuation in lipopolysaccharide-mediated oxidative stress in zebrafish." @default.
• W2743111064 created "2017-08-17" @default.
• W2743111064 creator A5008717028 @default.
• W2743111064 creator A5028717349 @default.
• W2743111064 creator A5078341118 @default.
• W2743111064 creator A5088552597 @default.
• W2743111064 date "2017-08-23" @default.
• W2743111064 modified "2023-10-14" @default.
• W2743111064 title "Improved Aromatic Substitution–Rearrangement-Based Ratiometric Fluorescent Cysteine-Specific Probe and Its Application of Real-Time Imaging under Oxidative Stress in Living Zebrafish" @default.
• W2743111064 cites W1664335312 @default.
• W2743111064 cites W1968903270 @default.
• W2743111064 cites W1977812252 @default.
• W2743111064 cites W1981883990 @default.
• W2743111064 cites W1983480912 @default.
• W2743111064 cites W1983847563 @default.
• W2743111064 cites W1984759027 @default.
• W2743111064 cites W1986984562 @default.
• W2743111064 cites W2011139685 @default.
• W2743111064 cites W2018339027 @default.
• W2743111064 cites W2019296000 @default.
• W2743111064 cites W2024422280 @default.
• W2743111064 cites W2028786217 @default.
• W2743111064 cites W2037172741 @default.
• W2743111064 cites W2037451324 @default.
• W2743111064 cites W2042746966 @default.
• W2743111064 cites W2056869450 @default.
• W2743111064 cites W2076283703 @default.
• W2743111064 cites W2076367848 @default.
• W2743111064 cites W2096062863 @default.
• W2743111064 cites W2110783613 @default.
• W2743111064 cites W2119817499 @default.
• W2743111064 cites W2135692925 @default.
• W2743111064 cites W2141779868 @default.
• W2743111064 cites W2148700883 @default.
• W2743111064 cites W2167666266 @default.
• W2743111064 cites W2272073014 @default.
• W2743111064 cites W2320572254 @default.
• W2743111064 cites W2324411030 @default.
• W2743111064 cites W2511725620 @default.
• W2743111064 cites W2514279849 @default.
• W2743111064 cites W2551497480 @default.
• W2743111064 cites W2564381097 @default.
• W2743111064 cites W2590951650 @default.
• W2743111064 cites W2603412875 @default.
• W2743111064 cites W2604419334 @default.
• W2743111064 cites W2618850006 @default.
• W2743111064 cites W2624585061 @default.
• W2743111064 cites W2626248632 @default.
• W2743111064 doi "https://doi.org/10.1021/acs.analchem.7b02649" @default.
• W2743111064 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28791863" @default.
• W2743111064 hasPublicationYear "2017" @default.
• W2743111064 type Work @default.
• W2743111064 sameAs 2743111064 @default.
• W2743111064 citedByCount "103" @default.
• W2743111064 countsByYear W27431110642018 @default.
• W2743111064 countsByYear W27431110642019 @default.
• W2743111064 countsByYear W27431110642020 @default.
• W2743111064 countsByYear W27431110642021 @default.
• W2743111064 countsByYear W27431110642022 @default.
• W2743111064 countsByYear W27431110642023 @default.
• W2743111064 crossrefType "journal-article" @default.
• W2743111064 hasAuthorship W2743111064A5008717028 @default.
• W2743111064 hasAuthorship W2743111064A5028717349 @default.
• W2743111064 hasAuthorship W2743111064A5078341118 @default.
• W2743111064 hasAuthorship W2743111064A5088552597 @default.
• W2743111064 hasConcept C104317684 @default.
• W2743111064 hasConcept C121332964 @default.
• W2743111064 hasConcept C12554922 @default.
• W2743111064 hasConcept C178790620 @default.
• W2743111064 hasConcept C181199279 @default.
• W2743111064 hasConcept C185592680 @default.
• W2743111064 hasConcept C2776151105 @default.
• W2743111064 hasConcept C2776878037 @default.
• W2743111064 hasConcept C2778004101 @default.
• W2743111064 hasConcept C2779201268 @default.
• W2743111064 hasConcept C2781338262 @default.
• W2743111064 hasConcept C538909803 @default.
• W2743111064 hasConcept C55493867 @default.
• W2743111064 hasConcept C62520636 @default.
• W2743111064 hasConcept C86803240 @default.
• W2743111064 hasConcept C91881484 @default.
• W2743111064 hasConcept C96305047 @default.
• W2743111064 hasConceptScore W2743111064C104317684 @default.
• W2743111064 hasConceptScore W2743111064C121332964 @default.
• W2743111064 hasConceptScore W2743111064C12554922 @default.
• W2743111064 hasConceptScore W2743111064C178790620 @default.
• W2743111064 hasConceptScore W2743111064C181199279 @default.
• W2743111064 hasConceptScore W2743111064C185592680 @default.
• W2743111064 hasConceptScore W2743111064C2776151105 @default.
• W2743111064 hasConceptScore W2743111064C2776878037 @default.
• W2743111064 hasConceptScore W2743111064C2778004101 @default.
• W2743111064 hasConceptScore W2743111064C2779201268 @default.
• W2743111064 hasConceptScore W2743111064C2781338262 @default.
• W2743111064 hasConceptScore W2743111064C538909803 @default.
• W2743111064 hasConceptScore W2743111064C55493867 @default.
• W2743111064 hasConceptScore W2743111064C62520636 @default.
• W2743111064 hasConceptScore W2743111064C86803240 @default.
• W2743111064 hasConceptScore W2743111064C91881484 @default.

• next