Matches in SemOpenAlex for { <https://semopenalex.org/work/W2743131417> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2743131417 endingPage "1455" @default.
- W2743131417 startingPage "1455" @default.
- W2743131417 abstract "Purpose: To obtain and evaluate carbopol hydrogel/sorbitan monostearate-almond oil-based organogel biphasic formulations (bigels) as a semi-solid vehicle for medicated topical applications.Methods: Bigel formulations were obtained under mild conditions at a hydrogel/organogel ratio of 80/20, 70/30, and 60/40 (w/w). Their stability, viscosity, spreadability, microarchitecture, and acute skin toxicity were evaluated.Results: Two formulations, prepared at ratios of 80/20 and 70/30, were stable based on intermediate stability testing, and had a similar viscosity and spreadability (38.0 ± 1.0 mm and 37.3 ± 0.6 mm, p > 0.05, respectively). Both of these formulations had a bimodal droplet size distribution and very similar values for the droplet mean diameter (0.33 ± 0.05 μm and 2.35 ± 0.44; and 0.34 ± 0.04 μm and 2.59 ± 0.21 μm). The formulation obtained at a ratio of 60/40 was unstable during storage. The in vivo results did not reveal any signs of skin toxicity.Conclusion: Considering their beneficial properties, the developed bigels are a potential semi-solid vehicle for topical application and exhibit a moisturizing effect.Keywords: Almond oil, Bigels, Carbopol hydrogel, Moisturizing effect, Organogel, Sorbitan monostearate" @default.
- W2743131417 created "2017-08-17" @default.
- W2743131417 creator A5010462168 @default.
- W2743131417 creator A5024619488 @default.
- W2743131417 creator A5028922686 @default.
- W2743131417 creator A5037715563 @default.
- W2743131417 creator A5067445668 @default.
- W2743131417 creator A5069192724 @default.
- W2743131417 date "2017-08-02" @default.
- W2743131417 modified "2023-10-15" @default.
- W2743131417 title "Carbopol hydrogel/sorbitan monostearate-almond oil based organogel biphasic formulations: Preparation and characterization of the bigels" @default.
- W2743131417 cites W1717555677 @default.
- W2743131417 cites W1967274764 @default.
- W2743131417 cites W1978396467 @default.
- W2743131417 cites W1989689456 @default.
- W2743131417 cites W1999904314 @default.
- W2743131417 cites W2007219286 @default.
- W2743131417 cites W2013674580 @default.
- W2743131417 cites W2030903809 @default.
- W2743131417 cites W2037231778 @default.
- W2743131417 cites W2044192035 @default.
- W2743131417 cites W2057751674 @default.
- W2743131417 cites W2083573686 @default.
- W2743131417 cites W2094204007 @default.
- W2743131417 cites W2113763680 @default.
- W2743131417 cites W2138778274 @default.
- W2743131417 cites W2298640928 @default.
- W2743131417 cites W2302926024 @default.
- W2743131417 cites W2520019715 @default.
- W2743131417 cites W632421197 @default.
- W2743131417 doi "https://doi.org/10.4314/tjpr.v16i7.1" @default.
- W2743131417 hasPublicationYear "2017" @default.
- W2743131417 type Work @default.
- W2743131417 sameAs 2743131417 @default.
- W2743131417 citedByCount "28" @default.
- W2743131417 countsByYear W27431314172018 @default.
- W2743131417 countsByYear W27431314172019 @default.
- W2743131417 countsByYear W27431314172020 @default.
- W2743131417 countsByYear W27431314172021 @default.
- W2743131417 countsByYear W27431314172022 @default.
- W2743131417 countsByYear W27431314172023 @default.
- W2743131417 crossrefType "journal-article" @default.
- W2743131417 hasAuthorship W2743131417A5010462168 @default.
- W2743131417 hasAuthorship W2743131417A5024619488 @default.
- W2743131417 hasAuthorship W2743131417A5028922686 @default.
- W2743131417 hasAuthorship W2743131417A5037715563 @default.
- W2743131417 hasAuthorship W2743131417A5067445668 @default.
- W2743131417 hasAuthorship W2743131417A5069192724 @default.
- W2743131417 hasBestOaLocation W27431314171 @default.
- W2743131417 hasConcept C127172972 @default.
- W2743131417 hasConcept C159985019 @default.
- W2743131417 hasConcept C178790620 @default.
- W2743131417 hasConcept C185592680 @default.
- W2743131417 hasConcept C192562407 @default.
- W2743131417 hasConcept C2780482525 @default.
- W2743131417 hasConcept C2781131970 @default.
- W2743131417 hasConcept C2781216929 @default.
- W2743131417 hasConcept C31903555 @default.
- W2743131417 hasConcept C43617362 @default.
- W2743131417 hasConcept C543025807 @default.
- W2743131417 hasConceptScore W2743131417C127172972 @default.
- W2743131417 hasConceptScore W2743131417C159985019 @default.
- W2743131417 hasConceptScore W2743131417C178790620 @default.
- W2743131417 hasConceptScore W2743131417C185592680 @default.
- W2743131417 hasConceptScore W2743131417C192562407 @default.
- W2743131417 hasConceptScore W2743131417C2780482525 @default.
- W2743131417 hasConceptScore W2743131417C2781131970 @default.
- W2743131417 hasConceptScore W2743131417C2781216929 @default.
- W2743131417 hasConceptScore W2743131417C31903555 @default.
- W2743131417 hasConceptScore W2743131417C43617362 @default.
- W2743131417 hasConceptScore W2743131417C543025807 @default.
- W2743131417 hasIssue "7" @default.
- W2743131417 hasLocation W27431314171 @default.
- W2743131417 hasOpenAccess W2743131417 @default.
- W2743131417 hasPrimaryLocation W27431314171 @default.
- W2743131417 hasRelatedWork W1977178782 @default.
- W2743131417 hasRelatedWork W2005197631 @default.
- W2743131417 hasRelatedWork W2059345844 @default.
- W2743131417 hasRelatedWork W2084726199 @default.
- W2743131417 hasRelatedWork W2092501151 @default.
- W2743131417 hasRelatedWork W2899084033 @default.
- W2743131417 hasRelatedWork W3005714394 @default.
- W2743131417 hasRelatedWork W3096581210 @default.
- W2743131417 hasRelatedWork W4205705015 @default.
- W2743131417 hasRelatedWork W4315498884 @default.
- W2743131417 hasVolume "16" @default.
- W2743131417 isParatext "false" @default.
- W2743131417 isRetracted "false" @default.
- W2743131417 magId "2743131417" @default.
- W2743131417 workType "article" @default.