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- W2743141635 abstract "In this paper, synephrine and phenylephrine compounds showed excellent inhibitory effects against human carbonic anhydrase (hCA) isoforms I and II, α-amylase, α-glycosidase, acetylcholinesterase (AChE), and butyrylcholinesterase (BChE). Synephrine and phenylephrine had Ki values of 199.02 ± 16.01 and 65.01 ± 5.00 μM against hCA I and 336.02 ± 74.01 and 92.04 ± 18.03 μM against hCA II, respectively. On the other hand, their Ki values were found to be 169.10 ± 80.03 and 88.03 ± 5.01 nM against AChE and 177.06 ± 6.01 and 78.03 ± 3.05 nM against BChE, respectively. α-Amylase and α-glycosidase enzymes were easily inhibited by these compounds. α-Glycosidase inhibitors, generally defined to as starch blockers, are anti-diabetic drugs that help to decrease post comestible blood glucose levels." @default.
- W2743141635 created "2017-08-17" @default.
- W2743141635 creator A5039363889 @default.
- W2743141635 creator A5050370140 @default.
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- W2743141635 date "2017-08-11" @default.
- W2743141635 modified "2023-10-02" @default.
- W2743141635 title "Synephrine and phenylephrine act as α‐amylase, α‐glycosidase, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase enzymes inhibitors" @default.
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- W2743141635 doi "https://doi.org/10.1002/jbt.21973" @default.
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