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- W2743149552 abstract "This chapter discusses the protein molecules of different types of cells at different stages of development, the role played by these molecules in the changes that occur during development, and the control of the synthesis of these molecules. The development of an organism is accompanied by the changing pattern of proteins (both quantitative and qualitative) that reflects the differential gene activity and that the different cell types are associated with different patterns of proteins, again reflecting the differential gene activity. The proteins of Drosophila change during development and are different in different tissues or cells. The most essential proteins are found in all cells at all times, while most luxury proteins are found in limited cell types and at the limited stages of development. The chapter describes the effect of mutation on the protein pattern of developing Drosophila. Mutations, affecting the development of Drosophila, frequently lead to the absence of a protein. Different cell lines respond in a different way to external stimuli, as hormones. With the use of cell lines derived from the stocks carrying appropriate mutants, it may be possible to use these techniques to investigate the mechanism of hormone action and gene control. Finally, the immediate control of gene activity in response to an external stimulus can be investigated, either by the study of mutants that fail to respond to that stimulus or by selecting mutants of the cultured cells that fail to respond." @default.
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- W2743149552 date "1975-01-01" @default.
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- W2743149552 title "Chapter 6 Drosophila Antigens: Their Spatial and Temporal Distribution, Their Function and Control" @default.
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- W2743149552 doi "https://doi.org/10.1016/s0070-2153(08)60029-0" @default.
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