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• W2743153203 endingPage "E9" @default.
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• W2743153203 abstract "Background: Preterm infants often receive blood transfusions during hospitalization. Although transfusions are intended to enhance oxygen delivery, previous studies found decreases in tissue and mesenteric oxygen saturation during and after blood transfusions without changes in vital signs and hemoglobin oxygen saturation. Purpose: To study the effect of blood transfusions on regional mesenteric tissue oxygen saturation (rS o 2 ), hemoglobin saturation of oxygen (Sp o 2 ), and heart rate (HR) in premature infants. Method: A prospective, observational, nonrandomized study using a repeated-measures design was done to evaluate changes in physiologic variables (HR, Sp o 2 , rS o 2 ) before, during, and after a blood transfusion in premature infants. Results: A convenience sample of 30 infants with a mean gestational age of 25.5 (2.1) weeks was recruited. Repeated-measures analysis of variance found no significant differences in HR ( P = .06) and Sp o 2 ( P = .55) over time. However, significant differences occurred in rS o 2 over the 3 time periods ( P < .001). The rS o 2 increased during the transfusion from 40.3% to 41.5%, but decreased to 34.9% in the posttransfusion period. Pairwise comparisons revealed statistically significant mean rS o 2 differences between pretransfusion and posttransfusion ( P < .001), and during transfusion to posttransfusion ( P < .001) periods. Implications for Research: This study supports previous findings of perfusion changes during blood transfusions in preterm infants. Implications for Practice: Measuring mesenteric tissue oxygenation during blood transfusion in very low-birth-weight infants can potentially add another physiologic parameter to guide further clinical assessment and interventions during transfusions." @default.
• W2743153203 created "2017-08-17" @default.
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• W2743153203 date "2017-10-01" @default.
• W2743153203 modified "2023-09-27" @default.
• W2743153203 title "Assessment of Mesenteric Tissue Saturation, Oxygen Saturation, and Heart Rate Pre- and Post-Blood Transfusion in Very Low-Birth-Weight Infants Using Abdominal Site Near-Infrared Spectroscopy" @default.
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• W2743153203 doi "https://doi.org/10.1097/anc.0000000000000417" @default.
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