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- W2743176987 abstract "Objective To explore the relationship between glycometabolism and tardive dyskinesia in schizophrenia patients. Methods Thirty schizophrenia patients with TD and 32 without TD were recruited by using the Simpson dyskinesia scale. They were assessed with the Positive and Negative Symptom Scale ( PANSS ) and Abnormal Involuntary Movement Scale ( AIMS ) ( Chinese version ). The levels of FINS ( fasting insulin ), IRI( insulin resistance index ), GHB( glycolated hemoglobin )and FPG( fasting plasma glucose )were measured. The relationship between glycometabolism and TD was analysed. Results The levels of FPG were significantly higher in schizophrenia patients with TD [( 5.74 ± 1.36 )mmol/L] than the patients without TD[( 5.05 ± 0. 91 )mmol/L] ( F = 6. 619, P = 0. 013 ). The AIMS scores were positively correlated with levels of FINS( r = 0. 469, P ＜ 0. 05 ), FPG( r = 0. 512, P ＜ 0. 05 )and IRI( r = 0. 483, P ＜0. 05 ). Conclusions Glycometabolism may be involved in the pathophysiological process of TD.Key words: Dyskinesia, drug-induced; Schizophrenia; Insulin; Blood glucose; Insulin resistance; Hemoglobins" @default.
- W2743176987 created "2017-08-17" @default.
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- W2743176987 date "2011-02-05" @default.
- W2743176987 modified "2023-09-23" @default.
- W2743176987 title "Relationship between glycometabolism and tardive dyskinesia in schizophrenia patients" @default.
- W2743176987 doi "https://doi.org/10.3760/cma.j.issn.1006-7884.2011.01.012" @default.
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