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- W2743243096 abstract "Objective To study platelet-rich plasma (PRP) by regulating the expression of Cyclin p27 promote fat stem cells to osteoblast differentiation mechanism.Methods By enzyme digestion rat adipose stem cells,PRP was observed in rat adipose stem cells into osteoblast differentiation.Flow cytometry PRP role and adipose stem cells on cell cycle and cell cycle proteins,Western blotting assay of cell cycle protein expression changes.Results PRP ADSCs intervention group was 41.0％ value-added,the blank control group added 7.4％.The proportion of S-phase ADSCs before induction increased from 26.5 percent to 67.9 percent.Conclusion PRP through down the cell cycle inhibitory protein,fat stem cells to improve the added value and differentiation rate,promoting fat stem cells into osteoblasts.Key words: Platelet-rich plasma; Adiposederived stem cells; Differentiation" @default.
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- W2743243096 date "2013-10-08" @default.
- W2743243096 modified "2023-09-23" @default.
- W2743243096 title "The research of platelet-rich plasma promote rat adipose stem cells to osteogenic differentiation by regulating cell cycle inhibitor p27" @default.
- W2743243096 doi "https://doi.org/10.3760/cma.j.issn.1001-9030.2013.10.061" @default.
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