Matches in SemOpenAlex for { <https://semopenalex.org/work/W2743334039> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2743334039 endingPage "314" @default.
- W2743334039 startingPage "314" @default.
- W2743334039 abstract "To determine whether S-1 induces hepatic steatosis in patients being treated for pancreatic cancer.This retrospective study evaluated 22 patients who received oral S-1 as a first-line treatment for pancreatic cancer between January 2008 and July 2015 at the Ishikawa Prefectural Central Hospital. Patients underwent abdominal computed tomography (CT) scans before chemotherapy and within 3 mo from the start of treatment. CT numbers of the liver and spleen were measured before and after S-1 administration. Steatosis was diagnosed when the ratio of the CT number of the liver to that of the spleen (liver/spleen ratio) was < 0.9.Median patient age was 68 years (range, 48-85 years), and median body mass index was 21 kg/m2 (range, 18-27 kg/m2). Of the 22 patients, six (27%) regularly consumed alcohol, and five (23%) had liver metastases. The mean ratio of CT number of the liver to the spleen was significantly higher before administration of S-1 (1.27 vs 1.09, P = 0.012) compared with after. Of the 22 patients, five (23%) had hepatic steatosis and 17 (77%) did not. The pretreatment demographic and clinical characteristics of these two groups showed no significant differences. The relationship between liver/spleen ratio and alanine transaminase activity in these patients. A statistically significant inverse correlation was observed (r = -0.417, P < 0.027).Of the 22 patients with pancreatic cancer, five (23%) experienced S-1 induced hepatic steatosis. Care should be taken during S-1 treatment of patients with pancreatic cancer." @default.
- W2743334039 created "2017-08-17" @default.
- W2743334039 creator A5022551435 @default.
- W2743334039 creator A5090906332 @default.
- W2743334039 date "2017-01-01" @default.
- W2743334039 modified "2023-09-25" @default.
- W2743334039 title "S-1 induced hepatic steatosis in patients with pancreatic cancer: Retrospective analysis" @default.
- W2743334039 cites W1587536571 @default.
- W2743334039 cites W1750163983 @default.
- W2743334039 cites W1975656082 @default.
- W2743334039 cites W1979114052 @default.
- W2743334039 cites W1995277697 @default.
- W2743334039 cites W2046843883 @default.
- W2743334039 cites W2077902459 @default.
- W2743334039 cites W2083353265 @default.
- W2743334039 cites W2121960517 @default.
- W2743334039 cites W2143953275 @default.
- W2743334039 cites W2171075804 @default.
- W2743334039 cites W2185043285 @default.
- W2743334039 cites W2326045278 @default.
- W2743334039 cites W2412717755 @default.
- W2743334039 cites W2417628796 @default.
- W2743334039 cites W2591717879 @default.
- W2743334039 doi "https://doi.org/10.4251/wjgo.v9.i8.314" @default.
- W2743334039 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5561042" @default.
- W2743334039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28868111" @default.
- W2743334039 hasPublicationYear "2017" @default.
- W2743334039 type Work @default.
- W2743334039 sameAs 2743334039 @default.
- W2743334039 citedByCount "2" @default.
- W2743334039 countsByYear W27433340392020 @default.
- W2743334039 countsByYear W27433340392022 @default.
- W2743334039 crossrefType "journal-article" @default.
- W2743334039 hasAuthorship W2743334039A5022551435 @default.
- W2743334039 hasAuthorship W2743334039A5090906332 @default.
- W2743334039 hasBestOaLocation W27433340391 @default.
- W2743334039 hasConcept C121608353 @default.
- W2743334039 hasConcept C126322002 @default.
- W2743334039 hasConcept C160160445 @default.
- W2743334039 hasConcept C167135981 @default.
- W2743334039 hasConcept C181199279 @default.
- W2743334039 hasConcept C185592680 @default.
- W2743334039 hasConcept C2776175330 @default.
- W2743334039 hasConcept C2776694085 @default.
- W2743334039 hasConcept C2778606649 @default.
- W2743334039 hasConcept C2778772119 @default.
- W2743334039 hasConcept C2779134260 @default.
- W2743334039 hasConcept C2779679107 @default.
- W2743334039 hasConcept C2780210213 @default.
- W2743334039 hasConcept C2780931953 @default.
- W2743334039 hasConcept C55493867 @default.
- W2743334039 hasConcept C71924100 @default.
- W2743334039 hasConcept C90924648 @default.
- W2743334039 hasConceptScore W2743334039C121608353 @default.
- W2743334039 hasConceptScore W2743334039C126322002 @default.
- W2743334039 hasConceptScore W2743334039C160160445 @default.
- W2743334039 hasConceptScore W2743334039C167135981 @default.
- W2743334039 hasConceptScore W2743334039C181199279 @default.
- W2743334039 hasConceptScore W2743334039C185592680 @default.
- W2743334039 hasConceptScore W2743334039C2776175330 @default.
- W2743334039 hasConceptScore W2743334039C2776694085 @default.
- W2743334039 hasConceptScore W2743334039C2778606649 @default.
- W2743334039 hasConceptScore W2743334039C2778772119 @default.
- W2743334039 hasConceptScore W2743334039C2779134260 @default.
- W2743334039 hasConceptScore W2743334039C2779679107 @default.
- W2743334039 hasConceptScore W2743334039C2780210213 @default.
- W2743334039 hasConceptScore W2743334039C2780931953 @default.
- W2743334039 hasConceptScore W2743334039C55493867 @default.
- W2743334039 hasConceptScore W2743334039C71924100 @default.
- W2743334039 hasConceptScore W2743334039C90924648 @default.
- W2743334039 hasIssue "8" @default.
- W2743334039 hasLocation W27433340391 @default.
- W2743334039 hasLocation W27433340392 @default.
- W2743334039 hasLocation W27433340393 @default.
- W2743334039 hasLocation W27433340394 @default.
- W2743334039 hasOpenAccess W2743334039 @default.
- W2743334039 hasPrimaryLocation W27433340391 @default.
- W2743334039 hasRelatedWork W2058103134 @default.
- W2743334039 hasRelatedWork W2169971207 @default.
- W2743334039 hasRelatedWork W2313710792 @default.
- W2743334039 hasRelatedWork W2341415937 @default.
- W2743334039 hasRelatedWork W2386988059 @default.
- W2743334039 hasRelatedWork W2800434881 @default.
- W2743334039 hasRelatedWork W3032463074 @default.
- W2743334039 hasRelatedWork W307921490 @default.
- W2743334039 hasRelatedWork W3176661137 @default.
- W2743334039 hasRelatedWork W4288451352 @default.
- W2743334039 hasVolume "9" @default.
- W2743334039 isParatext "false" @default.
- W2743334039 isRetracted "false" @default.
- W2743334039 magId "2743334039" @default.
- W2743334039 workType "article" @default.